Wang Jiajia, Dong Renfeng, Wu Huiying, Cai Yuepeng, Ren Biye
School of Chemistry and Environment, Guangzhou Key Laboratory of Materials for Energy Conversion and Storage, Guangdong Provincial Engineering Technology Research Center for Materials for Energy Conversion and Storage, South China Normal University, Guangzhou, 510006, People's Republic of China.
School of Materials Science and Engineering, South China University of Technology, Guangzhou, 510640, People's Republic of China.
Nanomicro Lett. 2019 Dec 30;12(1):11. doi: 10.1007/s40820-019-0350-5.
Micro/nanomotors have been extensively explored for efficient cancer diagnosis and therapy, as evidenced by significant breakthroughs in the design of micro/nanomotors-based intelligent and comprehensive biomedical platforms. Here, we demonstrate the recent advances of micro/nanomotors in the field of cancer-targeted delivery, diagnosis, and imaging-guided therapy, as well as the challenges and problems faced by micro/nanomotors in clinical applications. The outlook for the future development of micro/nanomotors toward clinical applications is also discussed. We hope to highlight these new advances in micro/nanomotors in the field of cancer diagnosis and therapy, with the ultimate goal of stimulating the successful exploration of intelligent micro/nanomotors for future clinical applications.
微纳马达已被广泛用于高效癌症诊断与治疗,基于微纳马达的智能综合生物医学平台设计取得的重大突破便是明证。在此,我们展示了微纳马达在癌症靶向递送、诊断及成像引导治疗领域的最新进展,以及微纳马达在临床应用中面临的挑战与问题。我们还讨论了微纳马达在临床应用方面未来发展的前景。我们希望突出微纳马达在癌症诊断与治疗领域的这些新进展,最终目标是推动对智能微纳马达进行成功探索,以用于未来临床应用。