Bampidis Vasileios, Azimonti Giovanna, Bastos Maria de Lourdes, Christensen Henrik, Dusemund Birgit, Fašmon Durjava Mojca, Kouba Maryline, López-Alonso Marta, López Puente Secundino, Marcon Francesca, Mayo Baltasar, Pechová Alena, Petkova Mariana, Ramos Fernando, Sanz Yolanda, Villa Roberto Edoardo, Woutersen Ruud, Anguita Montserrat, Galobart Jaume, Holczknecht Orsolya, Tarrés-Call Jordi, Pettenati Elisa, Pizzo Fabiola, Manini Paola
EFSA J. 2021 Jun 9;19(6):e06612. doi: 10.2903/j.efsa.2021.6612. eCollection 2021 Jun.
Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the assessment of the application for renewal of authorisation of vitamin B (pyridoxine hydrochloride) produced by chemical synthesis as a feed additive for all animal species. The applicant has provided data demonstrating that the additive in the market complies with the conditions of the authorisation. The FEEDAP Panel confirms that the use of pyridoxine hydrochloride under the current authorised conditions of use is safe for the target species, the consumers and the environment. Pyridoxine hydrochloride is non-irritant to skin and eyes. In the absence of data, no conclusion can be drawn on skin sensitisation potential. Pyridoxine hydrochloride may cause photosensitisation. Despite the lack of data on inhalation toxicity, the additive is not dusty and exposure through inhalation is unlikely. There is no need for assessing the efficacy of the additive in the context of the renewal of the authorisation.
应欧盟委员会的要求，动物饲料添加剂及产品或物质专家小组（FEEDAP）被要求就化学合成生产的维生素B（盐酸吡哆醇）作为所有动物物种饲料添加剂的授权续展申请评估发表科学意见。申请人提供的数据表明，市场上的该添加剂符合授权条件。FEEDAP小组确认，在当前授权使用条件下使用盐酸吡哆醇对目标物种、消费者和环境是安全的。盐酸吡哆醇对皮肤和眼睛无刺激性。由于缺乏数据，无法就皮肤致敏潜力得出结论。盐酸吡哆醇可能会引起光致敏作用。尽管缺乏吸入毒性数据，但该添加剂无粉尘，通过吸入接触的可能性不大。在授权续展的背景下，无需评估该添加剂的功效。
