Department of Radiology, Metabolism and Nutrition, Mayo Clinic, Rochester, Minnesota.
Department of Radiology, Metabolism and Nutrition, Mayo Clinic, Rochester, Minnesota.
J Vasc Interv Radiol. 2021 Sep;32(9):1288-1291. doi: 10.1016/j.jvir.2021.06.002. Epub 2021 Jun 16.
The outcomes of technically successful image-guided percutaneous thermal ablation of melanoma adrenal metastases involving 11 tumors in 9 consecutive patients over 12 years (2009-2020) were evaluated. All patients had multiple treated metastatic sites, and 44.4% (4/9) had greater than 5 metastatic sites. The mean maximal tumor diameter was 3.6 ± 1.6 cm. The local recurrence-free survival at 1 year was 85.7%. With a median survival of 19.4 months, 66.6% (6/9) of patients died from tumor progression. The 1- and 3-year overall survival rate was 60.0% and 30.0%, respectively. All patients were pretreated with alpha-adrenergic blockade, and 36% (4/11) developed a hypertensive crisis. The median hospital length of stay was 1 day (range, 1-2 days), without any major complications. Thermal ablation of adrenal metastasis from a melanoma provides acceptable local control and a good safety profile.
回顾性分析了 12 年间（2009-2020 年）连续 9 例 11 个病灶接受技术成功的影像引导经皮热消融治疗的黑色素瘤肾上腺转移瘤患者的结局。所有患者均存在多个转移病灶，44.4%（4/9）的患者存在大于 5 个转移病灶。最大肿瘤直径的平均值为 3.6±1.6cm。1 年局部无复发生存率为 85.7%。中位生存时间为 19.4 个月，66.6%（6/9）的患者因肿瘤进展而死亡。1 年和 3 年总生存率分别为 60.0%和 30.0%。所有患者均在术前接受α-肾上腺素能阻滞剂治疗，36%（4/11）发生高血压危象。中位住院时间为 1 天（范围：1-2 天），无严重并发症。热消融治疗黑色素瘤肾上腺转移瘤可获得可接受的局部控制和良好的安全性。
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