Rothman Orthopaedic Institute, Philadelphia, Pennsylvania, USA.
Universal Research Solutions LLC, Columbia, Missouri, USA.
Am J Sports Med. 2021 Jul;49(9):2426-2431. doi: 10.1177/03635465211021000. Epub 2021 Jun 23.
Patient-reported outcome measures (PROMs) are commonly used to monitor functional outcomes for clinical and research purposes; unfortunately, many PROMs include redundant, burdensome questions for patients. The use of predictive models to implement computerized adaptive testing (CAT) offer a potential solution to reduce question burden in outcomes research.
To validate the usage of an appropriate CAT system to improve the efficiency of the International Knee Documentation Committee (IKDC) Subjective Knee Form.
Cohort study (Diagnosis); Level of evidence, 2.
Validation was based on electronically collected patient responses from 2 separate orthopaedic sports medicine clinics. Diagnoses included, but were not limited to, meniscal lesions, ligamentous injuries, and chondral defects. The CAT system was previously developed through analysis of an electronic knee PROM database that did not contain any of these cases.
A total of 2173 patient responses (1229 patients) were collected. The CAT model was able to reduce the question burden by a mean of 9.33 questions (45.1%). Higher CAT-predicted scores correlated strongly with higher actual scores ( = 0.99; intraclass correlation coefficient = 0.99). The mean difference between the CAT-predicted score and the actual PROM score was 0.48 of a point on a scale of 0 to 100.
The use of CAT systems, in conjunction with electronic PROMs, can accurately predict outcome scores for IKDC PROMs, while dramatically decreasing the number of questionnaire items needed for any given patient. By decreasing questionnaire burden, clinicians and researchers can potentially increase patient participation and follow-up in both clinical assessments and research trials.
患者报告的结局测量(PROMs)常用于监测临床和研究目的的功能结局;遗憾的是,许多 PROMs 包含对患者来说冗余且繁琐的问题。使用预测模型来实施计算机化自适应测试(CAT)为减少结局研究中的问题负担提供了一种潜在的解决方案。
验证使用适当的 CAT 系统来提高国际膝关节文献委员会(IKDC)主观膝关节表格的效率。
队列研究(诊断);证据水平,2 级。
验证基于来自 2 个独立的矫形运动医学诊所的电子收集的患者应答。诊断包括但不限于半月板损伤、韧带损伤和软骨缺陷。CAT 系统是通过对不包含这些病例的电子膝关节 PROM 数据库的分析开发的。
共收集了 2173 名患者的应答(1229 名患者)。CAT 模型能够平均减少 9.33 个问题(45.1%)的问题负担。较高的 CAT 预测得分与较高的实际得分强烈相关(=0.99;组内相关系数=0.99)。CAT 预测得分与实际 PROM 得分之间的平均差值为 0 到 100 分的量表上的 0.48 分。
与电子 PROM 一起使用 CAT 系统可以准确预测 IKDC PROM 的结局得分,同时大大减少任何给定患者所需的问卷项目数量。通过减少问卷负担,临床医生和研究人员可以潜在地增加患者在临床评估和研究试验中的参与度和随访率。