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与新型冠状病毒2型感染相关的机化性肺炎

Organizing pneumonia associated with SARS-CoV-2 infection.

作者信息

Cortés Colorado Julián Mauricio, Cardona Ardila Luisa Fernanda, Aguirre Vásquez Natalia, Gómez Calderón Kevin Camilo, Lozano Álvarez Sandra Lucia, Carrillo Bayona Jorge Alberto

机构信息

Department of Internal Medicine. Universidad Javeriana de Cali, Colombia.

Department of Diagnostic Imaging, Universidad Nacional de Colombia. Hospital Universitario Nacional de Colombia, Colombia.

出版信息

Radiol Case Rep. 2021 Sep;16(9):2634-2639. doi: 10.1016/j.radcr.2021.06.028. Epub 2021 Jun 18.

DOI:10.1016/j.radcr.2021.06.028
PMID:34178186
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8213967/
Abstract

Organizing pneumonia is a nonspecific pulmonary response pattern associated with a variety of clinical contexts including viral infections. The classic radiological manifestations are peribronchovascular/peripheral ground glass opacities or consolidations and may be accompanied by nodules, masses, and interstitial opacities. We describe the case of a 62-year-old male patient with SARS-CoV-2 pneumonia and torpid clinical and radiological evolution in whom organizing pneumonia was documented through transbronchial biopsy and imaging findings, with a good response to corticosteroids. The importance of recognizing the development of organizing pneumonia lies in the better prognosis and outcome in those patients who receive treatment with corticosteroids, however, the clinical and radiological suspicion must be confirmed with biopsy because radiological findings associated with bacterial coinfection may overlap.

摘要

机化性肺炎是一种与多种临床情况相关的非特异性肺部反应模式,包括病毒感染。典型的放射学表现为支气管血管周围/外周磨玻璃影或实变,可能伴有结节、肿块和间质影。我们描述了一例62岁男性SARS-CoV-2肺炎患者,其临床和放射学进展缓慢,通过经支气管活检和影像学检查发现了机化性肺炎,对皮质类固醇治疗反应良好。认识到机化性肺炎的发生的重要性在于,接受皮质类固醇治疗的患者预后和结局较好,然而,临床和放射学怀疑必须通过活检来证实,因为与细菌合并感染相关的放射学表现可能重叠。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fbcd/8282955/ec169d0cbe5c/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fbcd/8282955/01f832888179/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fbcd/8282955/065e2a8de10c/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fbcd/8282955/10ccf9daf364/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fbcd/8282955/ec169d0cbe5c/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fbcd/8282955/01f832888179/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fbcd/8282955/065e2a8de10c/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fbcd/8282955/10ccf9daf364/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fbcd/8282955/ec169d0cbe5c/gr4.jpg

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本文引用的文献

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Persistent Pneumonic Consolidations due to Secondary Organizing Pneumonia in a Patient Recovering from COVID-19 Pneumonia: A Case Report and Literature Review.新冠病毒肺炎康复患者继发机化性肺炎导致的持续性肺实变:一例报告及文献综述
Infect Chemother. 2023 Mar;55(1):121-127. doi: 10.3947/ic.2022.0128. Epub 2023 Jan 9.
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Histopathological Findings in COVID-19 Cases: A Systematic Review.新型冠状病毒肺炎病例的组织病理学发现:一项系统综述
Cureus. 2022 Jun 1;14(6):e25573. doi: 10.7759/cureus.25573. eCollection 2022 Jun.
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Severe organising pneumonia following COVID-19.
COVID-19 后迟发性机化性肺炎的发生:3 例经支气管冷冻活检诊断病例报告及文献复习。
Intern Med. 2022 May 1;61(9):1403-1410. doi: 10.2169/internalmedicine.9016-21. Epub 2022 Mar 5.
COVID-19 后机化性肺炎。
Thorax. 2021 Feb;76(2):201-204. doi: 10.1136/thoraxjnl-2020-216088. Epub 2020 Nov 11.
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Chest CT in COVID-19: What the Radiologist Needs to Know.COVID-19 的胸部 CT:放射科医生需要了解的知识。
Radiographics. 2020 Nov-Dec;40(7):1848-1865. doi: 10.1148/rg.2020200159. Epub 2020 Oct 23.
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Coronavirus disease 2019-associated rapidly progressive organizing pneumonia with fibrotic feature: Two case reports.2019冠状病毒病相关的具有纤维化特征的快速进展性机化性肺炎:两例报告
Medicine (Baltimore). 2020 Aug 28;99(35):e21804. doi: 10.1097/MD.0000000000021804.
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Radiology-Pathology Correlation Demonstrating Organizing Pneumonia in a Patient Who Recovered from COVID-19.放射学与病理学相关性研究显示一名从新冠病毒疾病中康复的患者出现机化性肺炎。
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