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抽动障碍在整个生命周期中的病程。

Course of tic disorders over the lifespan.

作者信息

Black Kevin J, Kim Soyoung, Yang Nancy Y, Greene Deanna J

机构信息

Department of Psychiatry, Washington University in St. Louis School of Medicine, St. Louis, Missouri, 63110.

Department of Neurology, Washington University in St. Louis School of Medicine, St. Louis, Missouri, 63110.

出版信息

Curr Dev Disord Rep. 2021 Jun;8(2):121-132. doi: 10.1007/s40474-021-00231-3. Epub 2021 Apr 10.

Abstract

PURPOSE OF REVIEW

To summarize and update information on the course of tic disorders from childhood through later life.

RECENT FINDINGS

Tics tend to improve substantially over the first year after they appear. However, contrary to widespread opinion, tics usually last longer than one year, though usually at minimal severity. Tics often wane to clinical insignificance over the teen years, possibly resurging occasionally over the lifespan. However, in an important minority of patients, tics remain clinically relevant throughout life. Tics rarely first come to clinical attention later in adulthood, but new reports describe additional such cases.

SUMMARY

Recent publications have shown tics to persist past a few months more often than previously thought, though often at minimal severity, and recurrence after an asymptomatic period is common. The safety and efficacy of behavior therapy for tics, together with prospective indicators of early prognosis, make feasible the possibility of bettering the lifetime course of tic disorders with early intervention.

摘要

综述目的

总结并更新关于抽动障碍从儿童期到成年后期病程的信息。

最新发现

抽动症状出现后的第一年往往会有显著改善。然而,与普遍看法相反,抽动通常持续超过一年,尽管通常症状轻微。抽动症状在青少年时期常常减轻至临床无显著意义,可能在一生中偶尔复发。然而,在少数重要患者中,抽动在整个生命过程中都具有临床相关性。抽动很少在成年后期首次引起临床关注,但新的报告描述了更多此类病例。

总结

最近的出版物表明,抽动症状持续超过几个月的情况比以前认为的更常见,尽管通常症状轻微,并且在无症状期后复发很常见。抽动行为疗法的安全性和有效性,以及早期预后的前瞻性指标,使得通过早期干预改善抽动障碍的终生病程成为可能。

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