Vola J L, Petrakian J P, Mardrus R
Centre hospitalier de la Timone, Service du Pr Saracco, Marseille.
J Fr Ophtalmol. 1988;11(3):277-83.
The authors have checked absorbing U.V. IOLs. The use of these IOLs seems to be necessary because of the retinal damage due to direct exposure to near U.V., after lens extraction. Since about ten years a growing body of works has shown phototoxicity on lens and retina by U.V. radiation between 392 and 400 nm. This radiation transmitted by the cornea is not absorbed during the first decade. Progressively, cumulative effects of near U.V. on the lens involve fluorescent chromophore formations, pigmentation, and interferes with synthesis of lens proteins, catalyse insoluble proteins. Finally, cataract are produced as well as experimentally with U.V. lasers. In aphakic eyes the risk of retinal damage increases dramatically. Consequently IOLs absorbing U.V. radiation could protect the retina. A spectrographic check of U.V transmittance by standard IOLs and U.V. absorbing IOLs has shown that the U.V. absorbing IOLs block all radiations below 400 nm.
作者们对可吸收紫外线的人工晶状体进行了检查。由于晶状体摘除后直接暴露于近紫外线会导致视网膜损伤,使用这些人工晶状体似乎是必要的。大约十年来,越来越多的研究表明,波长在392至400纳米之间的紫外线辐射会对晶状体和视网膜产生光毒性。角膜透射的这种辐射在第一个十年中不会被吸收。逐渐地,近紫外线对晶状体的累积效应会导致荧光发色团形成、色素沉着,并干扰晶状体蛋白的合成,催化不溶性蛋白。最终,会像用紫外线激光进行实验那样产生白内障。在无晶状体眼中,视网膜损伤的风险会急剧增加。因此,可吸收紫外线辐射的人工晶状体可以保护视网膜。对标准人工晶状体和可吸收紫外线的人工晶状体的紫外线透过率进行光谱检查表明,可吸收紫外线的人工晶状体能阻挡所有低于400纳米的辐射。