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慢性烟草吸烟对成人神经心理学功能的负面影响:一项横断面研究。

The negative impact of chronic tobacco smoking on adult neuropsychological function: a cross-sectional study.

机构信息

Occupational Therapy Department, Faculty of Allied Health Sciences, Kuwait University, Jabriah, Kuwait.

School of Pharmacy and Pharmaceutical Sciences, Cardiff University, Cardiff, UK.

出版信息

BMC Public Health. 2021 Jun 30;21(1):1278. doi: 10.1186/s12889-021-11287-6.

Abstract

BACKGROUND

The evidence on the effects of chronic tobacco smoking on neuropsychological functions is conflicting. The literature remains limited by inconsistent accounting for potentially confounding biomedical and psychiatric conditions. This study aimed to assess the neuropsychological functions of adult chronic tobacco smokers in comparison to group-matched non-smokers.

METHOD

The study included 73 smokers and 84 group-matched non-smokers. The data was collected during the year 2019. After an initial interview to collect demographics and smoking profile, the subjects undertook neuropsychological assessments that targeted a wide range of cognitive domains.

RESULTS

The performance of smokers was poorer on almost all neuropsychological domains, namely selective attention (p ≤ .001, p = .044), alternating attention (p = .002) working memory (p ≤ .001), Short-term memory (p = .006 and .003), Long-term memory (p ≤ .001), processing accuracy (p ≤ .001), and executive function (p = .011 and .026). Smokers were intact on processing speed. Smoking accumulation and lower age onset of regular smoking were correlated with lower neuropsychological function.

CONCLUSION

Our findings add to the growing body of evidence suggesting that chronic tobacco smoking impacts cognition negatively.

摘要

背景

慢性吸烟对神经心理功能影响的证据存在争议。文献仍然受到潜在混杂的生物医学和精神状况不一致解释的限制。本研究旨在评估成年慢性吸烟者的神经心理功能,与匹配的非吸烟者进行比较。

方法

该研究纳入了 73 名吸烟者和 84 名匹配的非吸烟者。数据于 2019 年收集。在进行初始访谈以收集人口统计学和吸烟状况后,受试者进行了神经心理评估,针对广泛的认知领域。

结果

吸烟者在几乎所有神经心理领域的表现都较差,即选择性注意(p ≤.001,p =.044)、交替注意(p =.002)、工作记忆(p ≤.001)、短期记忆(p =.006 和.003)、长期记忆(p ≤.001)、处理准确性(p ≤.001)和执行功能(p =.011 和.026)。吸烟者在处理速度方面表现正常。吸烟积累和定期吸烟的较低年龄开始与较低的神经心理功能相关。

结论

我们的发现增加了越来越多的证据表明,慢性吸烟对认知有负面影响。

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