Kim Stacy J, Azour Lea, Hutchinson Barry D, Shirsat Hemlata, Zhou Fang, Narula Navneet, Moreira Andre L, Angel Luis, Ko Jane P, Moore William H
From the Department of Radiology (S.J.K., L.A., J.P.K., W.H.M.), Department of Pathology (F.Z., N.N., A.L.M.), Department of Pulmonology, Critical Care, and Sleep Medicine (L.A.), and Transplant Institute (L.A.), New York University, New York, NY; Department of Radiology, Mater Misericordiae University Hospital, Dublin, Ireland (B.D.H.); and Department of Pathology, Vancouver Island Health Authority and University of British Columbia, Victoria, British Columbia, Canada (H.S.).
Radiographics. 2021 Jul-Aug;41(4):1043-1063. doi: 10.1148/rg.2021200173.
Lung transplant is increasingly performed for the treatment of end-stage lung disease. As the number of lung transplants and transplant centers continues to rise, radiologists will more frequently participate in the care of patients undergoing lung transplant, both before and after transplant. Potential donors and recipients undergo chest radiography and CT as part of their pretransplant assessment to evaluate for contraindications to transplant and to aid in surgical planning. After transplant, recipients undergo imaging during the postoperative hospitalization and also in the long-term outpatient setting. Radiologists encounter a wide variety of conditions leading to end-stage lung disease and a myriad of posttransplant complications, some of which are unique to lung transplantation. Familiarity with these pathologic conditions, including their imaging findings and their temporal relationship to the transplant, is crucial to accurate radiologic interpretation. Knowledge of the surgical techniques and expected postoperative appearance prevents confusing normal posttransplant imaging findings with complications. A basic understanding of the indications, contraindications, and surgical considerations of lung transplant aids in imaging interpretation and protocoling and also facilitates communication between radiologists and transplant physicians. Despite medical and surgical advances over the past several decades, lung transplant recipients currently have an average posttransplant life expectancy of only 6.7 years. As members of the transplant team, radiologists can help maximize patient survival and hopefully increase posttransplant life expectancy and quality of life in the coming decades. RSNA, 2021 .
肺移植越来越多地用于治疗终末期肺病。随着肺移植数量和移植中心的不断增加,放射科医生将更频繁地参与肺移植患者移植前后的护理工作。潜在供体和受体在移植前评估时需进行胸部X线摄影和CT检查,以评估移植禁忌证并辅助手术规划。移植后,受体在术后住院期间以及长期门诊时都要接受影像学检查。放射科医生会遇到导致终末期肺病的多种情况以及众多移植后并发症,其中一些是肺移植特有的。熟悉这些病理状况,包括其影像学表现以及与移植的时间关系,对于准确的放射学解读至关重要。了解手术技术和预期的术后表现可避免将正常的移植后影像学表现与并发症相混淆。对肺移植的适应证、禁忌证和手术考量有基本了解有助于影像学解读和方案制定,也有助于放射科医生与移植医生之间的沟通。尽管在过去几十年里医学和外科技术取得了进步,但目前肺移植受体移植后的平均预期寿命仅为6.7年。作为移植团队的成员,放射科医生可以帮助最大限度地提高患者生存率,并有望在未来几十年提高移植后的预期寿命和生活质量。RSNA,2021年