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基于血管造影相的主动脉瓣钙化评分估计与计算机断层扫描中电离辐射剂量的降低

Estimation of Aortic Valve Calcium Score Based on Angiographic Phase Versus Reduction of Ionizing Radiation Dose in Computed Tomography.

作者信息

Gać Paweł, Kędzierski Bartłomiej, Macek Piotr, Pawlas Krystyna, Poręba Rafał

机构信息

Department of Hygiene, Wroclaw Medical University, Mikulicza-Radeckiego 7, PL 50-368 Wroclaw, Poland.

Centre for Diagnostic Imaging, 4th Military Hospital, Weigla 5, PL 50-981 Wroclaw, Poland.

出版信息

Life (Basel). 2021 Jun 23;11(7):604. doi: 10.3390/life11070604.

Abstract

The aim of the study was to evaluate the estimation efficacy of aortic valve calcium score (AVCS) based on the multislice computed tomography (MSCT) angiographic phase. The evaluation of the reduced amount of ionizing radiation dose was performed because of this estimation. The study included 51 consecutive patients who qualified for transcatheter aortic valve implantation (TAVI) (78.59 ± 5.72 years). All subjects underwent MSCT: in the native phase dedicated to AVCS as well as angiographic phases aimed to morphologically assess the aortic ostium and arterial accesses for TAVI. Based on the native phase, an AVCS assessment was performed for axial reconstructions at 3.0 mm and 2.0 mm slice thickness (AVCS and AVCS). Based on the angiographic phase AVCS was estimated for axial reconstruction at 0.6 mm slice thickness with increased values of lesion density in aortic valve cusps/aortic valve annulus, which is considered a calcification, from a typical value of 130 HU to 500 HU and 600 HU (AVCS and AVCS). Mathematical formulations were developed, allowing for AVCS native calculation based on AVCS values estimated based on the angiographic phase: AVCS = 813.920 + 1.510 AVCS; AVCS = 1235.863 + 1.817 AVCS; AVCS = 797.471 + 1.393 AVCS; AVCS = 1228.310 + 1.650 AVCS. The amount of a potential reduction in dose length product (DLP) in the case of AVCS estimation was 4.45 ± 1.54%. In summary, relying solely on the angiographic phase of MSCT examination before TAVI, it is possible to conclusively estimate AVCS. This estimation results in a marked reduction in radiation dose in MSCT.

摘要

本研究的目的是基于多层螺旋计算机断层扫描(MSCT)血管造影期评估主动脉瓣钙化评分(AVCS)的估算效能。由于此项估算,对降低电离辐射剂量进行了评估。该研究纳入了51例符合经导管主动脉瓣植入术(TAVI)条件的连续患者(年龄78.59±5.72岁)。所有受试者均接受了MSCT检查:在用于AVCS评估的平扫期以及旨在从形态学上评估主动脉口和TAVI动脉入路的血管造影期。基于平扫期,对层厚为3.0 mm和2.0 mm的轴向重建图像进行AVCS评估(AVCS和AVCS)。基于血管造影期,对层厚为0.6 mm的轴向重建图像进行AVCS估算,主动脉瓣叶/主动脉瓣环处病变密度值从典型的130 HU增加到500 HU和600 HU,这被视为钙化(AVCS和AVCS)。开发了数学公式,可根据基于血管造影期估算的AVCS值进行AVCS平扫期计算:AVCS = 813.920 + 1.510 AVCS;AVCS = 1235.863 + 1.817 AVCS;AVCS = 797.471 + 1.393 AVCS;AVCS = 1228.310 + 1.650 AVCS。在AVCS估算情况下,剂量长度乘积(DLP)潜在降低量为4.45±1.54%。总之,仅依靠TAVI术前MSCT检查的血管造影期,就可以确凿地估算AVCS。这种估算可显著降低MSCT的辐射剂量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ede9/8305341/ac5bdac63315/life-11-00604-g001.jpg

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