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社交距离、封锁措施与口罩的广泛使用;这是应对呼吸道病毒流行的神奇解决方案还是一把双刃剑?

Social Distancing, Lockdown and the Wide Use of Mask; A Magic Solution or a Double-Edged Sword for Respiratory Viruses Epidemiology?

作者信息

Sanz-Muñoz Ivan, Tamames-Gómez Sonia, Castrodeza-Sanz Javier, Eiros-Bouza José María, de Lejarazu-Leonardo Raul Ortiz

机构信息

National Influenza Centre, Edificio Rondilla, Hospital Clínico Universitario de Valladolid, 47009 Valladolid, Spain.

Dirección General de Salud Pública, Consejería de Sanidad, Junta de Castilla y León, 47001 Valladolid, Spain.

出版信息

Vaccines (Basel). 2021 Jun 3;9(6):595. doi: 10.3390/vaccines9060595.

Abstract

The use of non-pharmaceutical interventions (NPIs), such as social distancing, lockdowns and the massive use of masks, have not only largely prevented the spread of SARS-CoV-2, but also of other respiratory viruses such as influenza or respiratory syncytial virus (RSV). This decrease has been so high that, in most countries, the influenza and RSV epidemic has not occurred. Far from being a beneficial fact, this can be problematic, since the absence of circulation of certain pathogens can lead to a decrease in herd immunity against them. This can promote the rise of more serious, longer-lasting epidemics that start sooner. To alleviate the collateral effects that may occur due to the decrease in circulation of viruses such as influenza, it is necessary to increase the production of influenza vaccines, carry out mass vaccination campaigns and focus on vaccinating the main drivers of this virus, children.

摘要

使用非药物干预措施(NPIs),如保持社交距离、封锁以及大量使用口罩,不仅在很大程度上防止了严重急性呼吸综合征冠状病毒2(SARS-CoV-2)的传播,也防止了其他呼吸道病毒如流感病毒或呼吸道合胞病毒(RSV)的传播。这种传播减少幅度如此之大,以至于在大多数国家,流感和RSV疫情并未发生。这远非一个有益的情况,反而可能存在问题,因为某些病原体缺乏传播会导致针对它们的群体免疫力下降。这可能促使更严重、持续时间更长且更早开始的疫情爆发。为减轻因流感等病毒传播减少可能产生的附带影响,有必要增加流感疫苗的产量,开展大规模疫苗接种运动,并着重为该病毒的主要传播者儿童接种疫苗。

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