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心脏手术患者血液管理面临的挑战:一项叙述性综述

Challenges in Patient Blood Management for Cardiac Surgery: A Narrative Review.

作者信息

Rancati Valentina, Scala Emmanuelle, Ltaief Zied, Gunga Mohamed Ziyad, Kirsch Matthias, Rosner Lorenzo, Marcucci Carlo

机构信息

Department of Anesthesiology, University Hospital of Lausanne, Rue du Bugnon 46, 1011 Lausanne, Switzerland.

Department of Intensive Care Medicine, University Hospital of Lausanne, 1011 Lausanne, Switzerland.

出版信息

J Clin Med. 2021 Jun 1;10(11):2454. doi: 10.3390/jcm10112454.

Abstract

About 15 years ago, Patient Blood Management (PBM) emerged as a new paradigm in perioperative medicine and rapidly found support of all major medical societies and government bodies. Blood products are precious, scarce and expensive and their use is frequently associated with adverse short- and long-term outcomes. Recommendations and guidelines on the topic are published in an increasing rate. The concept aims at using an evidence-based approach to rationalize transfusion practices by optimizing the patient's red blood cell mass in the pre-, intra- and postoperative periods. However, elegant as a concept, the implementation of a PBM program on an institutional level or even in a single surgical discipline like cardiac surgery, can be easier said than done. Many barriers, such as dogmatic ideas, logistics and lack of support from the medical and administrative departments need to be overcome and each center must find solutions to their specific problems. In this paper we present a narrative overview of the challenges and updated recommendations for the implementation of a PBM program in cardiac surgery.

摘要

大约15年前,患者血液管理(PBM)作为围手术期医学的一种新范式出现,并迅速得到了所有主要医学协会和政府机构的支持。血液制品珍贵、稀缺且昂贵,其使用常常与不良的短期和长期后果相关。关于该主题的建议和指南发布的频率越来越高。这一概念旨在采用循证方法,通过在术前、术中和术后优化患者的红细胞量,使输血实践合理化。然而,尽管作为一个概念很不错,但在机构层面甚至在像心脏外科这样的单一外科领域实施PBM计划,说起来容易做起来难。许多障碍,如教条观念、后勤问题以及缺乏来自医疗和行政部门的支持等,都需要克服,每个中心都必须找到解决其特定问题的办法。在本文中,我们对心脏外科实施PBM计划的挑战和最新建议进行了叙述性概述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b13/8198483/2269a650ceae/jcm-10-02454-g001.jpg

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