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减重手术是否能降低未来的医院费用?利用英国生物库研究数据进行倾向评分匹配分析。

Does bariatric surgery reduce future hospital costs? A propensity score-matched analysis using UK Biobank Study data.

机构信息

Department of Family Medicine and Primary Care, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, Hong Kong SAR, China.

Health Economics Research Centre, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.

出版信息

Int J Obes (Lond). 2021 Oct;45(10):2205-2213. doi: 10.1038/s41366-021-00887-2. Epub 2021 Jul 1.

Abstract

OBJECTIVES

To estimate the hospital costs among persons with obesity undergoing bariatric surgery compared with those without bariatric surgery.

METHODS

We analysed the UK Biobank Cohort study linked to Hospital Episode Statistics, for all adults with obesity undergoing bariatric surgery at National Health Service hospitals in England, Scotland, or Wales from 2006 to 2017. Surgery patients were matched with controls who did not have bariatric surgery using propensity scores approach with a ratio of up to 1-to-5 by year. Inverse probability of censoring weighting was used to correct for potential informative censoring. Annual and cumulative hospital costs were assessed for the surgery and control groups.

RESULTS

We identified 348 surgical patients (198 gastric bypass, 73 sleeve gastrectomy, 77 gastric banding) during the study period. In total, 324 surgical patients and 1506 matched control participants were included after propensity score matching. Mean 5-year cumulative hospital costs were €11,659 for 348 surgical patients. Compared with controls, surgical patients (n = 324) had significantly higher inpatient expenditures in the surgery year (€7289 vs. €2635, P < 0.001), but lower costs in the subsequent 4 years. The 5-year cumulative costs were €11,176 for surgical patients and €8759 for controls (P = 0.001).

CONCLUSIONS

Bariatric surgery significantly increased the inpatient costs in the surgery year, but was associated with decreased costs in the subsequent 4 years. However, any cost savings made up to 4 years were not enough to compensate for the initial surgical expenditure.

摘要

目的

评估肥胖患者接受减重手术与未接受减重手术相比的住院费用。

方法

我们分析了英国生物库队列研究与医院入院统计数据的关联,纳入了 2006 年至 2017 年期间在英格兰、苏格兰或威尔士的国民保健制度医院接受减重手术的所有肥胖成年人。使用倾向评分匹配方法,按年份最多以 1:5 的比例将手术患者与未接受减重手术的对照组进行匹配。使用逆概率 censoring 加权法校正潜在的信息 censoring。评估手术组和对照组的年度和累积住院费用。

结果

研究期间,我们共发现 348 名手术患者(胃旁路手术 198 例,胃袖状切除术 73 例,胃带术 77 例)。经过倾向评分匹配后,共有 324 名手术患者和 1506 名匹配的对照组患者纳入研究。348 名手术患者的 5 年累积平均住院费用为 11659 欧元。与对照组相比,手术患者(n=324)在手术年度的住院支出显著更高(7289 欧元 vs. 2635 欧元,P<0.001),但在随后的 4 年中费用较低。手术患者的 5 年累积费用为 11176 欧元,对照组为 8759 欧元(P=0.001)。

结论

减重手术显著增加了手术年度的住院费用,但与随后 4 年的费用降低相关。然而,4 年内节省的任何费用都不足以弥补最初的手术支出。

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