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COVID-19 大规模遏制措施对老年人社区获得性肺炎发病率的间接影响:意大利托斯卡纳地区范围的基于人群的研究。

The indirect impact of COVID-19 large-scale containment measures on the incidence of community-acquired pneumonia in older people: a region-wide population-based study in Tuscany, Italy.

机构信息

Epidemiology Unit, Meyer Children's University Hospital, Viale Gaetano Pieraccini 24, 50139, Florence, Italy; Department of Health Sciences, University of Florence, Viale GB Morgagni 48, 50134, Florence, Italy.

Department of Health Sciences, University of Florence, Viale GB Morgagni 48, 50134, Florence, Italy.

出版信息

Int J Infect Dis. 2021 Aug;109:182-188. doi: 10.1016/j.ijid.2021.06.058. Epub 2021 Jul 1.

Abstract

OBJECTIVE

To evaluate the indirect effect of COVID-19 large-scale containment measures on the incidence of community-acquired pneumonia (CAP) in older people during the first epidemic wave of COVID-19 in Tuscany, Italy.

METHODS

A population-based study was carried out on data from the Tuscany healthcare system. The outcome measures were: hospitalization rate for CAP, severity of CAP hospitalizations, and outpatient consumption of antibacterials for CAP in people aged 65 and older. Outcomes were compared between corresponding periods in 2020 (week 1 to 27) and previous years.

RESULTS

Compared with the average of the corresponding periods in the previous 3 years, significant reductions in weekly hospitalization rates for CAP were observed from the week in which the national containment measures were imposed (week 10) until the end of the first COVID-19 wave in July (week 27). There was also a significant decrease in outpatient consumption in all antibacterial classes for CAP.

CONCLUSIONS

The implementation of large-scale COVID-19 containment measures likely reduced the incidence of CAP in older people during the first wave of the COVID-19 pandemic in Tuscany, Italy. Considering this indirect impact of pandemic containment measures on respiratory tract infections may improve the planning of health services during a pandemic in the future.

摘要

目的

评估意大利托斯卡纳地区 COVID-19 大规模封控措施对该地区 COVID-19 大流行第一波期间老年人社区获得性肺炎(CAP)发病率的间接影响。

方法

采用基于人群的研究方法,对托斯卡纳医疗保健系统的数据进行分析。结局指标包括:老年人因 CAP 住院的住院率、CAP 住院的严重程度和因 CAP 而在门诊使用的抗菌药物量。将 2020 年(第 10 周至第 27 周)相应时间段的结果与前几年同期进行比较。

结果

与前 3 年同期的平均值相比,从全国封控措施实施的第 10 周(第 10 周)到 7 月 COVID-19 第一波结束(第 27 周),每周 CAP 住院率显著下降。所有抗菌药物类别治疗 CAP 的门诊使用量也显著减少。

结论

意大利托斯卡纳地区 COVID-19 大规模封控措施的实施可能降低了 COVID-19 大流行第一波期间老年人 CAP 的发病率。考虑到大流行封控措施对呼吸道感染的这种间接影响,可能有助于未来在大流行期间更好地规划卫生服务。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6feb/8245306/44f2615b560d/gr1a_lrg.jpg

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