Ebbs S R, Saunders J A, Roberts J V, Baum M, Bates T, Morris J E
Department of Surgery, King's College Hospital, Rayne Institute, London.
J R Soc Med. 1988 Jan;81(1):13-4. doi: 10.1177/014107688808100107.
A low-intervention policy for Hickman catheter maintenance has been evaluated and found to be safe and cost effective. A simple, lightweight, disposable device has been used for 24-hour ambulatory home infusion. Implementation of this policy as part of a prospective randomized trial of single-agent chemotherapy in advanced breast cancer has demonstrated that slow intravenous infusion reduces the acute toxicity of epirubicin when compared with bolus injection.
一项关于希克曼导管维护的低干预政策已得到评估,结果表明该政策安全且具有成本效益。一种简单、轻便的一次性装置已用于24小时家庭门诊输液。作为晚期乳腺癌单药化疗前瞻性随机试验的一部分实施该政策,结果表明与推注相比,缓慢静脉输注可降低表柔比星的急性毒性。