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简化静脉输注化疗:初步交流

Simplifying infusion chemotherapy: preliminary communication.

作者信息

Ebbs S R, Saunders J A, Roberts J V, Baum M, Bates T, Morris J E

机构信息

Department of Surgery, King's College Hospital, Rayne Institute, London.

出版信息

J R Soc Med. 1988 Jan;81(1):13-4. doi: 10.1177/014107688808100107.

Abstract

A low-intervention policy for Hickman catheter maintenance has been evaluated and found to be safe and cost effective. A simple, lightweight, disposable device has been used for 24-hour ambulatory home infusion. Implementation of this policy as part of a prospective randomized trial of single-agent chemotherapy in advanced breast cancer has demonstrated that slow intravenous infusion reduces the acute toxicity of epirubicin when compared with bolus injection.

摘要

一项关于希克曼导管维护的低干预政策已得到评估,结果表明该政策安全且具有成本效益。一种简单、轻便的一次性装置已用于24小时家庭门诊输液。作为晚期乳腺癌单药化疗前瞻性随机试验的一部分实施该政策,结果表明与推注相比,缓慢静脉输注可降低表柔比星的急性毒性。

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