Department of Diagnostic and Therapeutic Neuroradiology, F-54000, CHRU Nancy and IADI, INSERM U1254, F-54000, Université de Lorraine, Nancy, France (F.Z., B.G., R.A.).
GHU Paris Psychiatrie et Neurosciences, Hospitalier Sainte Anne, Service d'imagerie Morphologique et Fonctionnelle, Institut de Psychiatrie et Neurosciences de Paris (IPNP), UMR_S1266, INSERM, Université de Paris (W.B.H., B.K., D.T., C.R.R., O.N., G.B.).
Stroke. 2021 Aug;52(9):2736-2742. doi: 10.1161/STROKEAHA.120.031940. Epub 2021 Jul 8.
We aimed to evaluate among trained interventional neuroradiologist, whether increasing individual experience was associated with an improvement in mechanical thrombectomy (MT) procedural performance metrics.
Individual MT procedural data from 5 centers of the Endovascular Treatment in Ischemic Stroke registry and 2 additional high-volume stroke centers were pooled. Operator experience was defined for each operator as a continuous variable, cumulating the number of MT procedures performed since January 2015, as MT became standard of care or, if later than this date, since the operator started performing mechanical thrombectomies in autonomy. We tested the associations between operator's experience and procedural metrics.
A total of 4516 procedures were included, performed by 36 operators at 7 distinct centers, with a median of 97.5 endovascular treatment procedures per operator (interquartile range, 57-170.2) over the study period. Higher operator's experience, analyzed as a continuous variable, was associated with a significantly shorter procedural duration (β estimate, -3.98 [95% CI, -5.1 to -2.8]; <0.001), along with local anesthesia and M1 occlusion location in multivariable models. Increasing experience was associated with better Thrombolysis in Cerebral Infarction scores (estimate, 1.02 [1-1.04]; =0.013).
In trained interventional neuroradiologists, increasing experience in MT is associated with significantly shorter procedural duration and better reperfusion rates, with a theoretical ceiling effect observed after around 100 procedures. These results may inform future training and practice guidelines to set minimal experience standards before autonomization, and to set-up operators' recertification processes tailored to individual case volume and prior experience.
我们旨在评估经过培训的神经介入放射医师中,个体经验的增加是否与机械血栓切除术(MT)程序性能指标的改善相关。
将来自缺血性卒中血管内治疗登记研究的 5 个中心和另外 2 个高容量卒中中心的个体 MT 程序数据进行汇总。为每位操作者定义了操作经验,该经验是自 2015 年 1 月以来实施 MT 手术的连续变量,此时 MT 已成为标准治疗方法,或者,如果在此日期之后,操作者开始自主进行机械血栓切除术。我们检验了操作者经验与程序指标之间的关联。
共纳入 4516 例手术,由 7 个不同中心的 36 名操作者完成,在研究期间,每位操作者的中位数为 97.5 例血管内治疗手术(四分位距,57-170.2)。作为连续变量分析的更高的操作者经验与显著较短的手术持续时间相关(β估计值,-3.98 [95%CI,-5.1 至-2.8];<0.001),并且在多变量模型中与局部麻醉和 M1 闭塞位置相关。经验的增加与更好的脑梗死溶栓评分相关(估计值,1.02 [1-1.04];=0.013)。
在经过培训的神经介入放射医师中,MT 经验的增加与手术持续时间显著缩短和更好的再灌注率相关,在大约 100 例手术后观察到理论上限效应。这些结果可能为未来的培训和实践指南提供信息,以便在自主化之前设定最低经验标准,并根据个体病例量和先前经验为操作者制定再认证流程。