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小儿正颌外科学:围手术期并发症的全国性分析。

Pediatric Orthognathic Surgery: National Analysis of Perioperative Complications.

机构信息

Division of Plastic and Reconstructive Surgery, Children's Hospital of Philadelphia, Philadelphia.

Department of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, PA.

出版信息

J Craniofac Surg. 2021;32(8):e798-e804. doi: 10.1097/SCS.0000000000007843.

Abstract

BACKGROUND

Orthognathic surgery has traditionally been performed after skeletal maturity. Although these procedures are also being performed in children, the implications of earlier intervention and specific risk factors in this younger population remain unknown.

METHODS

The American College of Surgeons National Surgical Quality Improvement Program Pediatric dataset was queried for orthognathic procedures performed in 2018. Complications, readmissions, and reoperations were analyzed with appropriate statistics.

RESULTS

Overall adverse event rate after orthognathic surgery in pediatric patients was 7.8% (n = 22 of 281), which were associated with having any comorbidity (P < 0.001), overall respiratory comorbidities (P = 0.004), structural pulmonary abnormality (P < 0.001), developmental delay (P = 0.035), structural central nervous system abnormality (P < 0.001), and neuromuscular disorder (P = 0.035). Most common complications were excessive bleeding (2.5%), surgical site infection (1.1%), and pneumonia (0.7%). Orthognathic surgery in children below 6 years of age is associated with significantly increased adverse events (P < 0.001), including surgical site infection (P < 0.001), pneumonia (P = 0.022), readmission (P < 0.001), and reoperation (P < 0.001). Le Fort I osteotomies (P < 0.001) and bilateral sagittal split osteotomies (P = 0.009) took significantly longer for older patients in the years of permanent dentition than younger patients in the years of deciduous dentition. Single- and double-jaw procedures in pediatric patients have similarly low adverse events (P all ≥0.130). Interestingly, bilateral sagittal split osteotomies performed before 13.5 years of age were associated with a higher risk of adverse events (P = 0.012), such that these younger patients were 7.1 times more likely to experience adverse events if their procedure was performed earlier.

CONCLUSIONS

Orthognathic surgery is relatively safe, but children in the years of deciduous dentition under 6 years of age have significantly increased risk of adverse events.

摘要

背景

正颌手术传统上是在骨骼成熟后进行的。尽管这些手术也在儿童中进行,但在这个更年轻的人群中,早期干预的影响和特定的风险因素仍不清楚。

方法

美国外科医师学会国家手术质量改进计划儿科数据集被查询了 2018 年进行的正颌手术。采用适当的统计学方法分析并发症、再入院和再次手术。

结果

在儿科患者中,正颌手术后的总体不良事件发生率为 7.8%(281 例中有 22 例),与存在任何合并症(P<0.001)、总体呼吸系统合并症(P=0.004)、结构性肺异常(P<0.001)、发育迟缓(P=0.035)、结构性中枢神经系统异常(P<0.001)和神经肌肉疾病(P=0.035)有关。最常见的并发症是过度出血(2.5%)、手术部位感染(1.1%)和肺炎(0.7%)。6 岁以下儿童的正颌手术与显著增加的不良事件相关(P<0.001),包括手术部位感染(P<0.001)、肺炎(P=0.022)、再入院(P<0.001)和再次手术(P<0.001)。在恒牙期,老年患者的 Le Fort I 截骨术(P<0.001)和双侧矢状劈开截骨术(P=0.009)明显长于乳牙期的年轻患者。儿童的单颌和双颌手术同样具有较低的不良事件(P 均≥0.130)。有趣的是,在 13.5 岁之前进行的双侧矢状劈开截骨术与不良事件风险增加相关(P=0.012),如果手术较早进行,这些年轻患者发生不良事件的可能性增加 7.1 倍。

结论

正颌手术相对安全,但 6 岁以下乳牙期的儿童不良事件风险显著增加。

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