Zhang Lanzeng, Li Xue, Zhang Xiyue, Li Yingjie, Wang Lushan
State Key Laboratory of Microbial Technology, Shandong University, Qingdao, 266237, China.
Biotechnol Biofuels. 2021 Jul 18;14(1):158. doi: 10.1186/s13068-021-02007-8.
Brown macroalgae have attracted great attention as an alternative feedstock for biorefining. Although direct conversion of ethanol from alginates (major components of brown macroalgae cell walls) is not amenable for industrial production, significant progress has been made not only on enzymes involved in alginate degradation, but also on metabolic pathways for biorefining at the laboratory level. In this article, we summarise recent advances on four aspects: alginate, alginate lyases, different alginate-degrading systems, and application of alginate lyases and associated pathways. This knowledge will likely inspire sustainable solutions for further application of both alginate lyases and their associated pathways.
褐藻作为生物精炼的替代原料已引起了广泛关注。尽管从藻酸盐（褐藻细胞壁的主要成分）直接转化乙醇并不适合工业生产，但不仅在参与藻酸盐降解的酶方面，而且在实验室水平的生物精炼代谢途径方面都取得了显著进展。在本文中，我们总结了四个方面的最新进展：藻酸盐、藻酸裂解酶、不同的藻酸盐降解系统以及藻酸裂解酶和相关途径的应用。这些知识可能会为藻酸裂解酶及其相关途径的进一步应用带来可持续的解决方案。
