首例中国患者足部糖尿病感染昆氏库克菌病例报告。
First Chinese case report of Helcococcus kunzii in a patient with diabetic foot.
机构信息
Clinical Laboratory, the First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China.
Center for Medical Experiments, University of Chinese Academy of Science-Shenzhen Hospital, Shenzhen, China.
出版信息
BMC Infect Dis. 2021 Jul 20;21(1):695. doi: 10.1186/s12879-021-06309-y.
BACKGROUND
Infection of Helcococcus kunzii(H. kunzii) from diabetic foot wound is rarely reported. This case report describes the infection of H.kunzii and highlights the therapeutic effect on H.kunzii from a diabetic foot wound.
CASE PRESENTATION
In this study, one H. kunzii strain was isolated from a patient with diabetic foot, which was confirmed by 16S rRNA gene analysis and MALDI-TOF-MS. It is the first Chinese case of H. kunzii in a patient with diabetic foot. As a result of the lack of antibiotic sensitivity data and multiple comorbidities, antibiotics were used cautiously, and those administered during the first 3 months were ineffective. Then, vacuum sealing drainage (VSD) was applied during hospitalization; no antibiotics were used and the wound healed well.
CONCLUSIONS
VSD alone may be more effective in treating diabetic feet infected with H. kunzii, which may provide reference for clinical treatment of H. kunzii infection from diabetic foot.
背景
从糖尿病足伤口感染 Helcococcus kunzii（H. kunzii）的情况很少见。本病例报告描述了 H.kunzii 的感染，并强调了其对糖尿病足伤口 H.kunzii 的治疗效果。
病例介绍
在这项研究中，从一名糖尿病足患者中分离出一株 H. kunzii，通过 16S rRNA 基因分析和 MALDI-TOF-MS 得到证实。这是中国首例糖尿病足患者的 H. kunzii 感染病例。由于缺乏抗生素敏感性数据和多种合并症，抗生素的使用谨慎，前 3 个月使用的抗生素无效。随后，在住院期间应用了真空密封引流（VSD）；未使用抗生素，伤口愈合良好。
结论
单独使用 VSD 可能更有效地治疗感染 H. kunzii 的糖尿病足，这可能为临床治疗糖尿病足 H. kunzii 感染提供参考。
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