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原发性开角型青光眼患者的健康相关生活质量。

HEALTH-RELATED QUALITY OF LIFE IN PRIMARY OPEN-ANGLE GLAUCOMA PATIENTS.

机构信息

1Department of Ophthalmology, Mostar University Hospital, Mostar, Bosnia and Herzegovina; 2Department of Physiology, School of Medicine, University of Mostar, Mostar, Bosnia and Herzegovina.

出版信息

Acta Clin Croat. 2020 Dec;59(4):623-631. doi: 10.20471/acc.2020.59.04.08.

Abstract

The purpose of this research was to evaluate the relationship between general health-related quality of life (GHRQL) and sociodemographic factors in primary open-angle glaucoma (POAG) patients. A prospective cross-sectional study included 207 glaucoma patients. GHRQL was determined two self-administered questionnaires: the 36-Item Short Form Survey (SF-36) and the EuroQol-5D (EQ-5D) questionnaire. Male and 50- to 69-year-old glaucoma patients, followed by patients who regularly used antiglaucoma therapy and those without progression of glaucoma reported a significantly higher quality of life as measured by the EQ-5D index and the EQ-5D visual analog scale (VAS) (p<0.05 all). Similarly, the Physical Component Summary (PCS) and Mental Component Summary (MCS) of SF-36 had significantly higher values for these patients (p<0.05 all). Furthermore, glaucoma patients with higher education and economic status, glaucoma patients who lived in rural areas, and those who were married achieved higher scores on EQ-5D and SF-36. In conclusion, progression of the disease, female sex, older age, lower education and economic status, urban area and unmarried status negatively affect quality of life in glaucoma patients.

摘要

本研究旨在评估原发性开角型青光眼(POAG)患者的一般健康相关生活质量(GHRQL)与社会人口学因素之间的关系。一项前瞻性横断面研究纳入了 207 名青光眼患者。GHRQL 通过两个自我管理问卷进行评估:36 项简短健康调查(SF-36)和欧洲五维健康量表(EQ-5D)问卷。男性和 50-69 岁的青光眼患者、定期使用抗青光眼治疗的患者以及青光眼无进展的患者,其 EQ-5D 指数和 EQ-5D 视觉模拟量表(VAS)的生活质量评分显著更高(均 p<0.05)。同样,SF-36 的生理成分综合评分(PCS)和心理成分综合评分(MCS)对这些患者也有显著更高的评分(均 p<0.05)。此外,文化程度和经济地位较高的青光眼患者、居住在农村地区的青光眼患者以及已婚的青光眼患者,在 EQ-5D 和 SF-36 上的得分更高。总之,疾病的进展、女性、年龄较大、教育和经济地位较低、居住在城区以及未婚状态,对青光眼患者的生活质量有负面影响。

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