Gu Jianjun, Chen Ziying
Department of Cardiac Surgery, Second Hospital of Hebei Medical University, Shijiazhuang, 050000, People's Republic of China.
Risk Manag Healthc Policy. 2021 Jul 14;14:3013-3023. doi: 10.2147/RMHP.S296165. eCollection 2021.
To evaluate the clinical efficacy of hybrid surgery for Stanford type A aortic dissection.
Twenty-two patients with Stanford type A aortic dissection were selected. All patients had completed or undergone hybrid surgery, including extracorporeal circulation, treatment of proximal anastomosis of ascending aorta and the distal anastomosis of the ascending aorta, management of the branch vessels on the arch, aortic endovascular repair. This study analyzed the time of surgery and awake, blood transfusion during surgery, patient's drainage, complications and CTA of aorta was re-examined about one month after operation during patients follow-up.
All patients underwent the operation successfully. One patient died of renal failure after the operation. Two patients experienced postoperative neurological complications (anxiety and delirium). Renal function was abnormal in two patients, and one patient needed bedside blood filtration. The serum creatinine levels temporarily increased in seven patients. No stent migration was found during patient follow-up. There was no shift in the stents. The near end of the interlayer was well sealed, without leakage of contrast agent, and the false lumen near the stent was completely thrombosed. Compared with the pre-operative CTA, the true lumen was enlarged and the false lumen was reduced, and the false lumen was completely thrombosed in the proximal end and near the stent. Contrast media was seen in the false lumen.
One-stage hybrid surgery for Stanford type A aortic dissection can avoid deep hypothermic circulatory arrest, shorten operation time, reduce operation trauma, and reduce the incidence of postoperative complications. This treatment has a effective treatment effect in the short term. However, the limitations imposed by covered stent materials mean that the treatment's long-term effect is not yet clear, and further research is needed.
评估杂交手术治疗 Stanford A 型主动脉夹层的临床疗效。
选取 22 例 Stanford A 型主动脉夹层患者。所有患者均完成或接受了杂交手术,包括体外循环、升主动脉近端吻合及升主动脉远端吻合处理、主动脉弓分支血管处理、主动脉腔内修复术。本研究分析了手术时间及清醒时间、术中输血情况、患者引流量、并发症情况,并在患者随访期间于术后约 1 个月复查主动脉 CTA。
所有患者手术均成功。1 例患者术后死于肾衰竭。2 例患者出现术后神经并发症(焦虑和谵妄)。2 例患者肾功能异常,1 例患者需要床边血液滤过。7 例患者血清肌酐水平暂时升高。患者随访期间未发现支架移位。支架无偏移。夹层近端封闭良好,无造影剂渗漏,支架附近假腔完全血栓形成。与术前 CTA 相比,真腔扩大,假腔缩小,近端及支架附近假腔完全血栓形成。假腔内可见造影剂。
Stanford A 型主动脉夹层一期杂交手术可避免深低温停循环,缩短手术时间,减少手术创伤,降低术后并发症发生率。该治疗在短期内有较好的治疗效果。然而,覆膜支架材料的局限性意味着该治疗的长期效果尚不清楚,需要进一步研究。