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美国银屑病和银屑病关节炎所致工作缺勤和残疾:一项基于 2009 年至 2020 年理赔数据的回顾性研究。

Work absenteeism and disability associated with psoriasis and psoriatic arthritis in the USA-a retrospective study of claims data from 2009 TO 2020.

机构信息

Division of Rheumatology, Psoriatic Arthritis Program, Johns Hopkins University school of Medicine, Baltimore, MD, USA.

NYU School of Medicine, New York, NY, USA.

出版信息

Clin Rheumatol. 2021 Dec;40(12):4933-4942. doi: 10.1007/s10067-021-05839-9. Epub 2021 Jul 21.

Abstract

OBJECTIVES

To compare work absenteeism and short-term disability among adults with psoriasis or psoriatic arthritis (PsA), versus controls in the USA.

METHODS

Adults eligible for work absenteeism and/or short-term disability benefits between 1/1/2009 and 4/30/2020 were screened in the IBM® MarketScan® Commercial and Health and Productivity Management Databases. The following groups were defined: (1) psoriasis: ≥ 2 psoriasis diagnoses ≥ 30 days apart and no PsA diagnoses; (2) PsA: ≥ 2 PsA diagnoses ≥ 30 days apart; (3) control: absence of psoriasis and PsA diagnoses. Controls were matched to psoriasis and PsA patients based on age, gender, index year, and comorbidities. Non-recreational work absences and sick leaves were evaluated in absentee-eligible patients, and short-term disability was evaluated in short-term disability-eligible patients. Costs (in 2019 USD) associated with each type of work absence were evaluated.

RESULTS

4261 psoriasis and 616 PsA absentee-eligible and 25,213 psoriasis and 3480 PsA short-term disability-eligible patients were matched to controls. Average non-recreational work absence costs were $1681, $1657, and $1217 for the PsA, psoriasis, and control group, respectively. Compared with psoriasis patients and controls, more PsA patients had sick leaves after 1 year (56.2% versus 55.6% and 41.5%, p < 0.0001). Similarly, short-term disability was more frequent in PsA patients than psoriasis patients and controls at year one (8.8% versus 5.6% and 4.7%, p < 0.0001) and corresponding costs were higher ($605, $406, and $335 on average, p < 0.0001).

CONCLUSION

Annual work absenteeism and short-term disability were consistently greater among patients with PsA and psoriasis than controls, highlighting the substantial economic burden of psoriatic disease. Key points • Patients with PsA had greater short-term disability compared with patients with psoriasis and patients with neither psoriasis nor PsA. • Patients with PsA and patients with psoriasis incurred greater non-recreational work absences and sick leaves than patients with neither psoriasis nor PsA.

摘要

目的

比较美国银屑病或银屑病关节炎(PsA)患者与对照者的成年人工作缺勤和短期残疾情况。

方法

2009 年 1 月 1 日至 2020 年 4 月 30 日期间,在 IBM® MarketScan®商业和健康与生产力管理数据库中筛选符合工作缺勤和/或短期残疾福利条件的成年人。定义了以下组:(1)银屑病:≥2 次银屑病诊断≥30 天且无 PsA 诊断;(2)PsA:≥2 次 PsA 诊断≥30 天;(3)对照:无银屑病和 PsA 诊断。对照者根据年龄、性别、索引年和合并症与银屑病和 PsA 患者相匹配。在符合缺勤条件的患者中评估非休闲性缺勤和病假,在符合短期残疾条件的患者中评估短期残疾。评估每种类型的工作缺勤相关的费用(以 2019 年美元计)。

结果

4261 名银屑病和 616 名 PsA 缺勤合格患者和 25213 名银屑病和 3480 名 PsA 短期残疾合格患者与对照者相匹配。PsA、银屑病和对照组的非休闲性工作缺勤平均费用分别为 1681、1657 和 1217 美元。与银屑病患者和对照者相比,更多的 PsA 患者在 1 年后请病假(56.2%比 55.6%和 41.5%,p<0.0001)。同样,在第 1 年,PsA 患者的短期残疾发生率也高于银屑病患者和对照者(8.8%比 5.6%和 4.7%,p<0.0001),相应的费用也更高(平均分别为 605、406 和 335 美元,p<0.0001)。

结论

与对照者相比,PsA 患者和银屑病患者的年工作缺勤率和短期残疾率始终更高,这突出了银屑病疾病的巨大经济负担。关键点:

  • 与银屑病患者和无银屑病或 PsA 的患者相比,PsA 患者的短期残疾更严重。

  • 与无银屑病或 PsA 的患者相比,PsA 患者和银屑病患者的非休闲性缺勤和病假天数更多。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b5ef/8599387/c13a6f6aca14/10067_2021_5839_Fig1_HTML.jpg

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