Division of Rheumatology, Psoriatic Arthritis Program, Johns Hopkins University school of Medicine, Baltimore, MD, USA.
NYU School of Medicine, New York, NY, USA.
Clin Rheumatol. 2021 Dec;40(12):4933-4942. doi: 10.1007/s10067-021-05839-9. Epub 2021 Jul 21.
To compare work absenteeism and short-term disability among adults with psoriasis or psoriatic arthritis (PsA), versus controls in the USA.
Adults eligible for work absenteeism and/or short-term disability benefits between 1/1/2009 and 4/30/2020 were screened in the IBM® MarketScan® Commercial and Health and Productivity Management Databases. The following groups were defined: (1) psoriasis: ≥ 2 psoriasis diagnoses ≥ 30 days apart and no PsA diagnoses; (2) PsA: ≥ 2 PsA diagnoses ≥ 30 days apart; (3) control: absence of psoriasis and PsA diagnoses. Controls were matched to psoriasis and PsA patients based on age, gender, index year, and comorbidities. Non-recreational work absences and sick leaves were evaluated in absentee-eligible patients, and short-term disability was evaluated in short-term disability-eligible patients. Costs (in 2019 USD) associated with each type of work absence were evaluated.
4261 psoriasis and 616 PsA absentee-eligible and 25,213 psoriasis and 3480 PsA short-term disability-eligible patients were matched to controls. Average non-recreational work absence costs were $1681, $1657, and $1217 for the PsA, psoriasis, and control group, respectively. Compared with psoriasis patients and controls, more PsA patients had sick leaves after 1 year (56.2% versus 55.6% and 41.5%, p < 0.0001). Similarly, short-term disability was more frequent in PsA patients than psoriasis patients and controls at year one (8.8% versus 5.6% and 4.7%, p < 0.0001) and corresponding costs were higher ($605, $406, and $335 on average, p < 0.0001).
Annual work absenteeism and short-term disability were consistently greater among patients with PsA and psoriasis than controls, highlighting the substantial economic burden of psoriatic disease. Key points • Patients with PsA had greater short-term disability compared with patients with psoriasis and patients with neither psoriasis nor PsA. • Patients with PsA and patients with psoriasis incurred greater non-recreational work absences and sick leaves than patients with neither psoriasis nor PsA.
比较美国银屑病或银屑病关节炎(PsA)患者与对照者的成年人工作缺勤和短期残疾情况。
2009 年 1 月 1 日至 2020 年 4 月 30 日期间,在 IBM® MarketScan®商业和健康与生产力管理数据库中筛选符合工作缺勤和/或短期残疾福利条件的成年人。定义了以下组:(1)银屑病:≥2 次银屑病诊断≥30 天且无 PsA 诊断;(2)PsA:≥2 次 PsA 诊断≥30 天;(3)对照:无银屑病和 PsA 诊断。对照者根据年龄、性别、索引年和合并症与银屑病和 PsA 患者相匹配。在符合缺勤条件的患者中评估非休闲性缺勤和病假,在符合短期残疾条件的患者中评估短期残疾。评估每种类型的工作缺勤相关的费用(以 2019 年美元计)。
4261 名银屑病和 616 名 PsA 缺勤合格患者和 25213 名银屑病和 3480 名 PsA 短期残疾合格患者与对照者相匹配。PsA、银屑病和对照组的非休闲性工作缺勤平均费用分别为 1681、1657 和 1217 美元。与银屑病患者和对照者相比,更多的 PsA 患者在 1 年后请病假(56.2%比 55.6%和 41.5%,p<0.0001)。同样,在第 1 年,PsA 患者的短期残疾发生率也高于银屑病患者和对照者(8.8%比 5.6%和 4.7%,p<0.0001),相应的费用也更高(平均分别为 605、406 和 335 美元,p<0.0001)。
与对照者相比,PsA 患者和银屑病患者的年工作缺勤率和短期残疾率始终更高,这突出了银屑病疾病的巨大经济负担。关键点:
与银屑病患者和无银屑病或 PsA 的患者相比,PsA 患者的短期残疾更严重。
与无银屑病或 PsA 的患者相比,PsA 患者和银屑病患者的非休闲性缺勤和病假天数更多。