Cochrane South Africa, South African Medical Research Council, Parow Valley, 7501, Cape Town, South Africa.
Cochrane South Africa, South African Medical Research Council, Parow Valley, 7501, Cape Town, South Africa; Division of Epidemiology and Biostatistics, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, 7505, Cape Town, South Africa; School of Public Health and Family Medicine, Faculty of Health Sciences, University of Cape Town, Observatory, 7925, Cape Town, South Africa.
Curr Opin Immunol. 2021 Aug;71:111-116. doi: 10.1016/j.coi.2021.07.003. Epub 2021 Jul 12.
COVID-19 is a pandemic of unprecedented proportions in recent human history. Less than 18 months since the onset of the pandemic, there are close to two hundred million confirmed cases and four million deaths worldwide. There have also been massive efforts geared towards finding safe and effective vaccines. By July 2021 there were 184 COVID-19 vaccine candidates in pre-clinical development, 105 in clinical development, and 18 vaccines approved for emergency use by at least one regulatory authority. These vaccines include whole virus live attenuated or inactivated, protein-based, viral vector, and nucleic acid vaccines. By mid-2021 three billion doses of COVID-19 vaccine have been administered around the world, mostly in high-income countries. COVID-19 vaccination provides hope for an end to the pandemic, if and only if there would be equal access and optimal uptake in all countries around the world.
COVID-19 是人类近代历史上规模空前的大流行疾病。自大流行疾病爆发以来不到 18 个月，全球已确诊病例接近 2 亿例，死亡病例超过 400 万。同时，全世界也在不遗余力地开发安全有效的疫苗。截至 2021 年 7 月，有 184 种 COVID-19 疫苗候选药物处于临床前开发阶段，105 种处于临床开发阶段，至少有 18 种疫苗已获得至少一个监管机构的紧急使用授权。这些疫苗包括全病毒减毒活疫苗或灭活疫苗、基于蛋白的疫苗、病毒载体疫苗和核酸疫苗。截至 2021 年年中，全球已接种超过 30 亿剂 COVID-19 疫苗，其中大部分在高收入国家。如果全球各国都能平等获得疫苗并实现最佳接种，COVID-19 疫苗将为结束大流行带来希望。
Zotero 插件