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注意力缺陷/多动障碍与青年期酒精及其他物质使用障碍:一项加拿大全国代表性调查的结果

Attention-Deficit/Hyperactivity Disorder and Alcohol and Other Substance Use Disorders in Young Adulthood: Findings from a Canadian Nationally Representative Survey.

作者信息

Fuller-Thomson Esme, Lewis Danielle A, Agbeyaka Senyo

机构信息

Factor-Inwentash Faculty of Social Work, University of Toronto, 246 Bloor St. W., Toronto, Canada.

Department of Family and Community Medicine, 500 University Avenue, 5th Floor University of Toronto, Toronto, Canada.

出版信息

Alcohol Alcohol. 2022 May 10;57(3):385-395. doi: 10.1093/alcalc/agab048.

Abstract

AIM

(a) To document the prevalence and odds of (i) alcohol use disorders, (ii) cannabis use disorders, (iii) other drug use disorders and (iv) any substance use disorder (SUD), among young adults with and without ADHD, and (b) to investigate the degree to which the association between ADHD and SUDs is attenuated by socio-demographics, early adversities and mental health.

METHOD

Secondary analysis of the nationally representative Canadian Community Health Survey-Mental Health (CCHS-MH). The sample included 6872 respondents aged 20-39, of whom 270 had ADHD. The survey response rate was 68.9%.

MEASUREMENTS

Substance Use Disorder: World Health Organization's Composite International Diagnostic Interview criteria, SUDs, were derived from lifetime algorithms for alcohol, cannabis and other substance abuse or dependence. ADHD was based on self-report of a health professional's diagnosis.

FINDINGS

One in three young adults with ADHD had a lifetime alcohol use disorder (36%) compared to 19% of those without ADHD (P < 0.001). After adjusting for all control variables, those with ADHD had higher odds of developing alcohol use disorders (OR = 1.38, 95% CI: 1.05, 1.81), cannabis use disorders (OR = 1.46, 95% CI: 1.06, 2.00), other drug use disorders (OR = 2.07, 95% CI: 1.46, 2.95) and any SUD (OR = 1.69, 95% CI: 1.28, 2.23). History of depression and anxiety led to the largest attenuation of the ADHD-SUD relationship, followed by childhood adversities and socioeconomic status.

CONCLUSIONS

Young adults with ADHD have a high prevalence of alcohol and other SUDs. Targeted outreach and interventions for this extremely vulnerable population are warranted.

摘要

目的

(a)记录患有和未患有注意力缺陷多动障碍(ADHD)的年轻成年人中,(i)酒精使用障碍、(ii)大麻使用障碍、(iii)其他药物使用障碍以及(iv)任何物质使用障碍(SUD)的患病率和比值比;(b)调查社会人口统计学、早期逆境和心理健康在多大程度上减弱了ADHD与SUD之间的关联。

方法

对具有全国代表性的加拿大社区健康调查-心理健康(CCHS-MH)进行二次分析。样本包括6872名年龄在20至39岁之间的受访者,其中270人患有ADHD。调查回复率为68.9%。

测量方法

物质使用障碍:世界卫生组织的综合国际诊断访谈标准(SUD),源自酒精、大麻和其他物质滥用或依赖的终生算法。ADHD基于健康专业人员诊断的自我报告。

研究结果

三分之一患有ADHD的年轻成年人有终生酒精使用障碍(36%),而未患有ADHD的年轻成年人中这一比例为19%(P < 0.001)。在对所有控制变量进行调整后,患有ADHD的人发生酒精使用障碍(比值比=1.38,95%置信区间:1.05,1.81)、大麻使用障碍(比值比=1.46,95%置信区间:1.06,2.00)、其他药物使用障碍(比值比=2.07,95%置信区间:1.46,2.95)和任何SUD(比值比=1.69,95%置信区间:1.28,2.23)的几率更高。抑郁和焦虑史导致ADHD与SUD关系的减弱幅度最大,其次是童年逆境和社会经济地位。

结论

患有ADHD的年轻成年人中酒精和其他SUD的患病率很高。有必要针对这一极易受影响的人群进行有针对性的宣传和干预。

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