Padilla Ruiz Maykel Alain
Departamento de Gastroenterología. Hospital Universitario "Dr. Celestino Hernández Robau". Santa Clara, Villa Clara, Cuba.
Rev Gastroenterol Peru. 2021 Jan-Mar;41(1):21-26.
The early diagnosis of occult hepatic encephalopathy in patients with liver cirrhosis is currently a challenge, mainly with regard to diagnostic tests. Objetive: The aim of this study was to compare the results of two tests, the psychometric score for hepatic encephalopathy and the Stroop EncephalApp in the diagnosis of covert hepatic encephalopathy.
The two tests were applied in patients in the cirrhosis consultation of the "Arnaldo Milián" Hospital in Villa Clara, comparing the results of Stroop EncephalApp taking as reference the psychometric score for hepatic encephalopathy. The variables age, sex and schooling were adjusted according to population norms.
A total of 80 cirrhotic patients were included, as well as 520 healthy controls. Using the Stroop EncephalApp, 35% presented covert hepatic encephalopathy, when the Psychometric score for hepatic encephalopathy was used. The prevalence was 40%, showing the sensitivity of Stroop EncephalApp of 80% and 82% of specificity.
undiagnosed occult hepatic encephalopathy shows a high prevalence in cirrhosis. The psychometric score for hepatic encephalopathy and Stroop EncephalApp show adequate sensitivity in the diagnosis of occult hepatic encephalopathy.
肝硬化患者隐匿性肝性脑病的早期诊断目前是一项挑战,主要体现在诊断测试方面。目的:本研究旨在比较两种测试方法,即肝性脑病心理测量评分和Stroop脑病应用程序在隐匿性肝性脑病诊断中的结果。
这两种测试应用于比利亚克拉拉省“阿纳尔多·米利安”医院肝硬化门诊的患者,以肝性脑病心理测量评分为参照,比较Stroop脑病应用程序的结果。根据人群标准对年龄、性别和受教育程度等变量进行了调整。
共纳入80例肝硬化患者以及520例健康对照。使用Stroop脑病应用程序时,35%的患者存在隐匿性肝性脑病;使用肝性脑病心理测量评分时,患病率为40%,Stroop脑病应用程序的敏感性为80%,特异性为82%。
未诊断出的隐匿性肝性脑病在肝硬化中患病率较高。肝性脑病心理测量评分和Stroop脑病应用程序在隐匿性肝性脑病诊断中显示出足够的敏感性。