Phytochemistry Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Facultad de Ciencias de la Salud, Universidad Arturo Prat, Avda. Arturo Prat 2120, Iquique 1110939, Chile.
Oxid Med Cell Longev. 2021 Jul 24;2021:7571132. doi: 10.1155/2021/7571132. eCollection 2021.
The genus, generally well-known as licorice, is broadly used for food and medicinal purposes around the globe. The genus encompasses a rich pool of bioactive molecules including triterpene saponins (e.g., glycyrrhizin) and flavonoids (e.g., liquiritigenin, liquiritin). This genus is being increasingly exploited for its biological effects such as antioxidant, antibacterial, antifungal, anti-inflammatory, antiproliferative, and cytotoxic activities. The species L. and the compound glycyrrhizin (glycyrrhizic acid) have been studied immensely for their effect on humans. The efficacy of the compound has been reported to be significantly higher on viral hepatitis and immune deficiency syndrome. This review provides up-to-date data on the most widely investigated species for food and medicinal purposes, with special emphasis on secondary metabolites' composition and bioactive effects.
该属植物,通常被称为甘草,在全球范围内被广泛用于食品和医药用途。该属植物包含丰富的生物活性分子,包括三萜皂苷(如甘草甜素)和类黄酮(如甘草素、甘草苷)。由于其具有抗氧化、抗菌、抗真菌、抗炎、抗增殖和细胞毒性等生物活性,该属植物正被越来越多地开发利用。该属植物的许多种以及化合物甘草甜素(甘草酸)因其对人类的影响而被广泛研究。该化合物在治疗病毒性肝炎和免疫缺陷综合征方面的疗效被报道显著更高。本综述提供了关于最广泛用于食品和医药用途的种的最新数据,特别强调了次生代谢产物的组成和生物活性作用。