妇科癌症患者的血清维生素A、维生素E和胡萝卜素

Serum vitamins A and E and carotene in patients with gynecologic cancer.

作者信息

Heinonen P K, Kuoppala T, Koskinen T, Punnonen R

机构信息

Department of Obstetrics and Gynecology, Tampere University Central Hospital, Finland.

出版信息

Arch Gynecol Obstet. 1987;241(3):151-6. doi: 10.1007/BF00931311.

DOI:10.1007/BF00931311

PMID:3435184

Abstract

Serum concentrations of vitamin A (retinol), vitamin E (alpha-tocopherol) and total carotene were measured in 88 women with gynecologic cancer (9 vulvar, 15 cervical, 36 endometrial and 28 ovarian carcinomas) and 31 healthy controls. No significant differences were found in the serum levels of the vitamins and carotene in patients with vulvar, cervical or endometrial cancer compared to the controls. The patients with ovarian cancer had a significantly (P less than 0.01) lower mean serum level of vitamin A than the controls, while carotene and vitamin E level were similar in both groups. The results indicate that vitamin A may have a role in the metabolism of patients with advanced ovarian cancer.

摘要

对88名妇科癌症患者（9例外阴癌、15例宫颈癌、36例子宫内膜癌和28例卵巢癌）和31名健康对照者测定了血清维生素A（视黄醇）、维生素E（α-生育酚）和总胡萝卜素的浓度。与对照组相比，外阴癌、宫颈癌或子宫内膜癌患者的维生素和胡萝卜素血清水平未发现显著差异。卵巢癌患者的平均血清维生素A水平显著低于对照组（P<0.01），而两组的胡萝卜素和维生素E水平相似。结果表明，维生素A可能在晚期卵巢癌患者的代谢中起作用。