Rosser B R Simon, Konety Badrinath R, Capistrant Benjamin D, Kapoor Aditya, Polter Elizabeth
Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA.
Department of Urology, University of Minnesota, Minneapolis, Minnesota, USA.
Urol Pract. 2020 May;7(3):224-227. doi: 10.1097/upj.0000000000000086. Epub 2020 May 1.
In two studies, gay, bisexual, and other men who have sex with men prostate cancer survivors report lower Gleason scores than heterosexual prostate cancer survivors, leading some to speculate that men who have sex with men may have more intensive screening than other men. In the largest study of men who have sex with men prostate cancer survivors to date, 23 of 193 (11.9%) men who have sex with men prostate cancer survivors reported low Gleason scores (2-5). We contacted 14 of them, a 61 percent response rate. At second interview, most men clarified that they reported only a partial score rather than the sum score. We conclude the average lower score is not a result of differences in screening but likely measurement error. A revised Gleason item question is provided to overcome this research artifact.
在两项研究中,男同性恋者、双性恋者及其他与男性发生性行为的男性前列腺癌幸存者报告的Gleason评分低于异性恋前列腺癌幸存者,这使得一些人推测,与男性发生性行为的男性可能比其他男性接受了更密集的筛查。在迄今为止针对与男性发生性行为的男性前列腺癌幸存者的最大规模研究中,193名与男性发生性行为的男性前列腺癌幸存者中有23人(11.9%)报告了低Gleason评分(2 - 5分)。我们联系了其中14人,回复率为61%。在第二次访谈中,大多数男性澄清说他们报告的只是部分评分而非总分。我们得出结论,平均较低的评分不是筛查差异的结果,而可能是测量误差。提供了一个修订后的Gleason项目问题以克服这一研究假象。