COVID-19 相关嗅觉障碍患者也表现出三叉神经功能受损。
Patients with COVID-19-associated olfactory impairment also show impaired trigeminal function.
机构信息
Department of Otorhinolaryngology, Head and Neck Surgery, University of Cologne, Medical Faculty, Cologne 50924, Germany.
Department of Otorhinolaryngology, Head and Neck Surgery, University of Cologne, Medical Faculty, Cologne 50924, Germany.
出版信息
Auris Nasus Larynx. 2022 Feb;49(1):147-151. doi: 10.1016/j.anl.2021.07.012. Epub 2021 Jul 26.
OBJECTIVE
Next to olfactory function, the nose can also perceive chemestetic sensations mediated by the trigeminal nerve. While olfactory dysfunction as a symptom of COVID-19 is well described, there has been little research on the limitation of other nasal sensory inputs due to SARS-CoV-2 infection. The aim of this study was to determine possible limitations of nasal chemesthesis after COVID-19 infection by a psychophysiological diagnostic tool.
METHODS
In 65 patients with a PCR-confirmed, former COVID-19 disease, olfaction was tested by means of a sniffin' sticks test, tasting by taste sprays and chemesthesis with a menthol dilution series. The subjective self-assessment of the patients was recorded via a questionnaire.
RESULTS
We found a restriction of nasal chemesthesis and the extent correlated with the loss of smell, as well as with the values of the taste score, but not with subjective self-assessment.
CONCLUSION
Not only the ability to smell and taste, but also nasal chemesthesis is affected by COVID-19.
目的
除了嗅觉功能外，鼻子还可以感知三叉神经介导的化学感觉。虽然 COVID-19 作为一种症状的嗅觉功能障碍已得到充分描述，但由于 SARS-CoV-2 感染，对其他鼻腔感觉输入的限制的研究很少。本研究旨在通过心理生理学诊断工具确定 COVID-19 感染后鼻腔化学感觉可能受到的限制。
方法
在 65 名经 PCR 确诊的 COVID-19 患者中，通过嗅探棒测试、味觉喷雾测试和薄荷醇稀释系列测试来测试嗅觉。通过问卷调查记录患者的主观自我评估。
结果
我们发现鼻腔化学感觉受限，其程度与嗅觉丧失以及味觉评分的数值相关，但与主观自我评估无关。
结论
不仅嗅觉和味觉能力，而且鼻腔化学感觉也受到 COVID-19 的影响。
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