亨廷顿舞蹈病的姿势与步态研究方法
Approach to Posture and Gait in Huntington's Disease.
作者信息
Talman Lauren S, Hiller Amie L
机构信息
Department of Neurology, Oregon Health & Science University, Portland, OR, United States.
Portland VA Healthcare System, Portland, OR, United States.
出版信息
Front Bioeng Biotechnol. 2021 Jul 27;9:668699. doi: 10.3389/fbioe.2021.668699. eCollection 2021.
Abstract
Disturbances of gait occur in all stages of Huntington's disease (HD) including the premanifest and prodromal stages. Individuals with HD demonstrate the slower speed of gait, shorter stride length, and increased variability of gait parameters as compared to controls; cognitive disturbances in HD often compound these differences. Abnormalities of gait and recurrent falls lead to decreased quality of life for individuals with HD throughout the disease. This scoping review aims to outline the cross-disciplinary approach to gait evaluation in HD and will highlight the utility of objective measures in defining gait abnormalities in this patient population.
摘要
亨廷顿舞蹈症（HD）的各个阶段都会出现步态障碍，包括临床前期和前驱期。与对照组相比，HD患者表现出步态速度较慢、步幅较短以及步态参数变异性增加；HD患者的认知障碍往往会加剧这些差异。步态异常和反复跌倒导致HD患者在整个病程中的生活质量下降。本综述旨在概述HD步态评估的跨学科方法，并将强调客观测量在定义该患者群体步态异常中的作用。
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本文引用的文献
1
Quantifying Postural Control in Premanifest and Manifest Huntington Disease Using Wearable Sensors.
Neurorehabil Neural Repair. 2020 Sep;34(9):771-783. doi: 10.1177/1545968320939560. Epub 2020 Jul 16.
2
Multiple Wearable Sensors in Parkinson and Huntington Disease Individuals: A Pilot Study in Clinic and at Home.
Digit Biomark. 2017 Aug 17;1(1):52-63. doi: 10.1159/000479018. eCollection 2017 Sep-Dec.
3
Gait variability as digital biomarker of disease severity in Huntington's disease.
J Neurol. 2020 Jun;267(6):1594-1601. doi: 10.1007/s00415-020-09725-3. Epub 2020 Feb 11.
4
The effects of dual-task cognitive interference on gait and turning in Huntington's disease.
PLoS One. 2020 Jan 7;15(1):e0226827. doi: 10.1371/journal.pone.0226827. eCollection 2020.
5
Clinical recommendations to guide physical therapy practice for Huntington disease.
Neurology. 2020 Feb 4;94(5):217-228. doi: 10.1212/WNL.0000000000008887. Epub 2020 Jan 6.
6
The Effects of Dual-Task Cognitive Interference and Environmental Challenges on Balance in Huntington's Disease.
Mov Disord Clin Pract. 2019 Jan 16;6(3):202-212. doi: 10.1002/mdc3.12720. eCollection 2019 Mar.
7
Gait, balance, and falls in Huntington disease.
Handb Clin Neurol. 2018;159:251-260. doi: 10.1016/B978-0-444-63916-5.00016-1.
8
Computerised Dynamic Posturography in Premanifest and Manifest individuals with Huntington's Disease.
Sci Rep. 2018 Oct 2;8(1):14615. doi: 10.1038/s41598-018-32924-y.
9
Biological and clinical manifestations of juvenile Huntington's disease: a retrospective analysis.
Lancet Neurol. 2018 Nov;17(11):986-993. doi: 10.1016/S1474-4422(18)30294-1. Epub 2018 Sep 19.
10
Effects of multidisciplinary therapy on physical function in Huntington's disease.
Acta Neurol Scand. 2018 Dec;138(6):500-507. doi: 10.1111/ane.13002. Epub 2018 Jul 30.
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