心房电机械延迟和 P 波离散度与慢性阻塞性肺疾病严重程度的关系。
Atrial electromechanical delay and p wave dispersion associated with severity of chronic obstructive pulmonary disease.
机构信息
Department of Cardiology, Kırıkkale Yuksek Ihtisas Hospital, Kırıkkale, Turkey.
Department of Cardiology, Medical Faculty of Kırıkkale University, Kırıkkale, Turkey.
出版信息
Afr Health Sci. 2021 Mar;21(1):140-149. doi: 10.4314/ahs.v21i1.19.
BACKGROUND
The aim of this study was to evaluate atrial electromechanical delay (AEMD) with both electrocardiography (ECG) and echocardiography in patients with Chronic Obstructive Pulmonary Disease (COPD).
METHODS
Total of 110 patients were included in this cross-sectional case-control study. P-wave dispersion (PWD) was measured on a 12-lead ECG. Atrial electromechanical intervals (PA) were measured as the time interval between the onset of the P wave on the ECG and the beginning of the late diastolic A wave.
RESULTS
PWD was found to be 40.9±9.2 ms in the healthy control group, 45.6±8.2 ms in the mild COPD and 44.8±8.7 ms in the severe COPD group (p<0.05). Intra-right atrial EMD was found to be 10.7±5.8 ms in mild COPD, 11.0±7 ms in severe COPD, and it was 16.4±7.3 ms in healthy control group (p<0.001). Interatrial EMD was detected to be 29.5±9.1 ms in the control group, 24.1±9 ms in mild COPD group, and 23.9±11.1 ms in the severe COPD group (p<0.001).
CONCLUSION
Both mild and severe COPD groups decreased PWD, increased tricuspid PA and significantly decreased interand right intra-AEMD times in comparison to the control group.
背景
本研究旨在评估慢性阻塞性肺疾病（COPD）患者的心电图（ECG）和超声心动图的心房机电延迟（AEMD）。
方法
本横断面病例对照研究共纳入 110 例患者。在 12 导联心电图上测量 P 波离散度（PWD）。心房机电间隔（PA）测量为心电图上 P 波起始与舒张晚期 A 波起始之间的时间间隔。
结果
健康对照组的 PWD 为 40.9±9.2ms，轻度 COPD 组为 45.6±8.2ms，重度 COPD 组为 44.8±8.7ms（p<0.05）。轻度 COPD 组右心房内 EMD 为 10.7±5.8ms，重度 COPD 组为 11.0±7ms，健康对照组为 16.4±7.3ms（p<0.001）。对照组的房间隔 EMD 为 29.5±9.1ms，轻度 COPD 组为 24.1±9ms，重度 COPD 组为 23.9±11.1ms（p<0.001）。
结论
与对照组相比，轻度和重度 COPD 组均降低了 PWD，增加了三尖瓣 PA，并显著缩短了房间隔和右心房内 AEMD 时间。
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