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80 岁及以上超高龄患者腰椎融合术的疗效:与 65 岁及以上和 80 岁以下患者的比较。

Outcomes of lumbar spinal fusion in super-elderly patients aged 80 years and over: Comparison with patients aged 65 years and over, and under 80 years.

机构信息

Department of Orthopedic Surgery, Hanyang University College of Medicine, Seoul, Korea.

Department of Orthopedic Surgery, Hanyang University, College of Medicine, Guri Hospital, Gyeonggi, Korea.

出版信息

Medicine (Baltimore). 2021 Aug 6;100(31):e26812. doi: 10.1097/MD.0000000000026812.

Abstract

Despite the increasing prevalence of spinal surgery in super-elderly (SE) patients, the outcomes and complication rates have not been fully elucidated. The purpose of this study was to compare the outcomes and complications of lumbar spinal fusion for degenerative lumbar spinal stenosis (DLSS) in SE patients aged 80 years and over with those in patients aged 65 years and over, and under 80 years.This study analyzed 160 patients who underwent spinal fusion for DLSS between January 2011 and November 2019. Thirty patients in the SE group (group SE, ≥80 years) and 130 patients in the elderly group (group E, ≥65 years and <80 years) were enrolled. The performance status was evaluated by preoperative American society of anesthesiologists (ASA) score. Visual analog scales for back pain (VAS-BP) and leg pain (VAS-LP), and Korean Oswestry disability index (K-ODI) were used to assess clinical outcomes preoperatively and 1 year postoperatively. Percent changes of VAS-BP, VAS-LP and K-ODI were also analyzed. Fusion rates were evaluated by computed tomography 6 months and 1 year postoperatively. Furthermore, bone mineral density, operative time, estimated blood loss, blood transfusion, hospital days, hospitalization in intensive care unit and postoperative complications were compared.The average age of group SE was 82.0 years and that of group E was 71.6 years. There were no differences in preoperative ASA score, preoperative or postoperative VAS BP and VAS-LP, bone mineral density, operative time, estimated blood loss, blood transfusion, hospital days, hospitalization in intensive care unit and fusion rates between the groups. Preoperative and postoperative K-ODI were higher in group SE than group E (all P < .05). However, percent changes of VAS-BP, VAS-LP and K-ODI showed no significant differences. Overall early and late complications were not significantly different between the groups; however postoperative delirium was more common in group SE than group E (P = .027). SE status was the only risk factor for postoperative delirium with odds ratio of 3.4 (P = .018).Spinal fusion surgery is considerable treatment to improve the quality of life of SE patients with DLSS, however careful perioperative management is needed to prevent postoperative delirium.

摘要

尽管高龄(SE)患者脊柱手术的发病率不断增加,但手术结果和并发症发生率尚未完全阐明。本研究旨在比较 80 岁及以上 SE 患者与 65 岁及以上、80 岁以下患者行腰椎融合术治疗退行性腰椎管狭窄症(DLSS)的手术结果和并发症。本研究分析了 2011 年 1 月至 2019 年 11 月期间接受腰椎融合术治疗 DLSS 的 160 例患者。SE 组(年龄≥80 岁,组 SE)30 例,老年组(年龄≥65 岁且<80 岁,组 E)130 例。术前美国麻醉医师协会(ASA)评分评估患者的功能状态。术前及术后 1 年采用视觉模拟评分(VAS)评估腰痛(VAS-BP)和腿痛(VAS-LP),采用韩国 Oswestry 残疾指数(K-ODI)评估临床疗效。还分析了 VAS-BP、VAS-LP 和 K-ODI 的百分比变化。术后 6 个月和 1 年通过 CT 评估融合率。此外,比较了两组的骨密度、手术时间、估计失血量、输血、住院天数、入住重症监护病房天数和术后并发症。SE 组的平均年龄为 82.0 岁,E 组的平均年龄为 71.6 岁。两组间术前 ASA 评分、术前和术后 VAS-BP 和 VAS-LP、骨密度、手术时间、估计失血量、输血、住院天数、入住重症监护病房天数和融合率均无差异。SE 组术前和术后 K-ODI 均高于 E 组(均 P<.05)。然而,VAS-BP、VAS-LP 和 K-ODI 的百分比变化无显著差异。两组的早期和晚期并发症总体无显著差异;然而,SE 组术后谵妄较 E 组更常见(P =.027)。SE 状态是术后谵妄的唯一危险因素,比值比为 3.4(P =.018)。脊柱融合术是改善高龄 DLSS 患者生活质量的一种重要治疗方法,但需要谨慎的围手术期管理,以预防术后谵妄。

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