在一宗有争议的亲子鉴定案中发现的谷氨酸丙酮酸转氨酶（GPT）变异体。

Glutamate-pyruvate transaminase (GPT) variant found in a disputed paternity case.

作者信息

Kumagai R, Tokiwa K, Nakayashiki N, Katsura S

机构信息

Department of Legal Medicine, School of Medicine, Iwate Medical University, Morioka.

出版信息

Tohoku J Exp Med. 1987 Dec;153(4):383-8. doi: 10.1620/tjem.153.383.

DOI:10.1620/tjem.153.383

PMID:3441928

Abstract

GPT variants, GPT2C-1 and GPT2A-2C, were found in samples from a mother and her child, respectively, in a disputed paternity case. The phenotype GPT 2C-1 was determined by polyacrylamide gel electrophoresis performed at alkaline pH and acidic pH; this is probably the first GPT*2C-1 detected in Japanese. It was considered that the GPT 2C allele in this family was inherited in a manner of autosomal codominant transmission.

摘要

在一宗有争议的亲子鉴定案件中，分别在一位母亲及其孩子的样本中发现了GPT变异体GPT2C - 1和GPT2A - 2C。GPT 2C - 1的表型是通过在碱性pH和酸性pH条件下进行的聚丙烯酰胺凝胶电泳确定的；这可能是在日本人中首次检测到的GPT*2C - 1。据认为，该家族中的GPT 2C等位基因是以常染色体共显性遗传的方式遗传的。