Silecchia Gianfranco, Iossa Angelo
Department of Medico-Surgical Sciences and Biotechnologies, Faculty of Pharmacy and Medicine, University of Rome 'Sapienza', Italy.
Expert Rev Endocrinol Metab. 2021 Sep;16(5):229-235. doi: 10.1080/17446651.2021.1967742. Epub 2021 Aug 23.
Laparoscopic sleeve gastrectomy is the most commonly performed bariatric procedure worldwide; due to its extensive impact and analysis, multiple procedure-related early and late complications have been described. Gastroesophageal reflux and Barrett's esophagus are highly debated issues related to sleeve gastrectomy in long-term follow-up. This review aims to explore the association between sleeve gastrectomy and gastroesophageal reflux in terms of their occurrence, and to analyze the protective or affecting factors.
Gastroesophageal reflux and Barrett's esophagus after laparoscopic sleeve gastrectomy.
Gastroesophageal reflux is the Achilles' heel of sleeve gastrectomy and is affected by multiple procedure-related functional or mechanical factors (intrathoracic migration, stenosis, lower esophageal sphincter incompetence). Its postoperative incidence is about 30% with significant variability among groups, especially in terms of preoperative workup (lack of routine upper gastro-intestinal endoscopy and symptom assessment). Strict patient selection and mandatory pre-operative endoscopy are the primary steps taken to prevent and reduce the incidence of post-operative severe gastroesophageal reflux. However, patients should also be informed of the possibility of the 'de novo gastroesophageal reflux disease' (incidence - 22-50%) and the need for surgical revision in selected cases (0.5-7%).
腹腔镜袖状胃切除术是全球最常用的减肥手术;由于其广泛的影响和分析,已经描述了多种与手术相关的早期和晚期并发症。胃食管反流和巴雷特食管是长期随访中与袖状胃切除术相关的备受争议的问题。本综述旨在探讨袖状胃切除术与胃食管反流在发生方面的关联,并分析保护或影响因素。
腹腔镜袖状胃切除术后的胃食管反流和巴雷特食管。
胃食管反流是袖状胃切除术的致命弱点,受多种与手术相关的功能或机械因素(胸腔内移位、狭窄、食管下括约肌功能不全)影响。其术后发生率约为30%,各群体之间存在显著差异,尤其是在术前检查方面(缺乏常规上消化道内镜检查和症状评估)。严格的患者选择和强制性术前内镜检查是预防和降低术后严重胃食管反流发生率的首要步骤。然而,也应告知患者“新发胃食管反流病”的可能性(发生率为22%-50%)以及在特定病例中进行手术修正的必要性(0.5%-7%)。