无麸质饮食对乳糜泻患者健康相关生活质量的影响。
The influence of a gluten-free diet on health-related quality of life in individuals with celiac disease.
机构信息
Clinical Nutrition Program, Department of Health Sciences, College of Health and Rehabilitation Sciences, Princess Nourah Bint Abdulrahman University (PNU), PO Box 84428, Riyadh, Kingdom of Saudi Arabia.
Department of Food and Nutrition, Faculty of Human Sciences and Design, King Abdulaziz University (KAU), Jeddah, Kingdom of Saudi Arabia.
出版信息
BMC Gastroenterol. 2021 Aug 25;21(1):330. doi: 10.1186/s12876-021-01908-0.
BACKGROUND
Adherence to a gluten-free diet (GFD) and food insecurity (FI) may influence health-related quality of life (HRQOL) in individuals with celiac disease (CD). This study aimed to investigate the association between adherence to a GFD, FI, and HRQOL in individuals with CD.
METHODS
This cross-sectional study included 97 adults (mean age: 34 ± 9 years) diagnosed with CD. The participants were on a GFD for more than 6 months. Sociodemographic characteristics and medical history were assessed. Adherence to a GFD, FI, and HRQOL were assessed using validated questionnaires.
RESULTS
Most participants (73%) adhered to a GFD, and 62% were experiencing FI. Individuals with CD faced difficulty in accessing GF foods due to the high cost (90%) and limited availability (79%). The mean overall HRQOL score was 60. Scores on the physical and mental health domains were 69 and 47, respectively. Adherence to a GFD was significantly associated with FI (P = 0.02), while there was no association between adherence to a GFD and HRQOL measures (P > 0.05). Participants facing FI had lower scores in emotional well-being and mental health domains, and overall HRQOL (P < 0.05).
CONCLUSIONS
The findings of the present study demonstrate that FI influences adherence to a GFD, and that FI is associated with HRQOL in terms of both emotional well-being and mental health.
背景
遵循无麸质饮食（GFD）和食物不安全（FI）可能会影响乳糜泻（CD）患者的健康相关生活质量（HRQOL）。本研究旨在探讨 CD 患者遵循 GFD、FI 和 HRQOL 之间的关联。
方法
这是一项横断面研究，共纳入 97 名成年（平均年龄：34 ± 9 岁）确诊为 CD 的患者。这些患者遵循 GFD 超过 6 个月。评估了社会人口统计学特征和病史。使用经过验证的问卷评估 GFD 依从性、FI 和 HRQOL。
结果
大多数参与者（73%）遵循 GFD，62%的人经历过 FI。由于高成本（90%）和有限的供应（79%），CD 患者在获得 GF 食品方面存在困难。整体 HRQOL 评分的平均值为 60。身体和心理健康领域的得分分别为 69 和 47。GFD 的依从性与 FI 显著相关（P=0.02），而 GFD 的依从性与 HRQOL 测量之间没有关联（P>0.05）。面临 FI 的参与者在情绪健康和心理健康领域以及整体 HRQOL 方面的得分较低（P<0.05）。
结论
本研究的结果表明，FI 影响 GFD 的依从性，FI 与情绪健康和心理健康方面的 HRQOL 相关。
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