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结节病中的单侧视网膜动脉炎和大动脉瘤

Unilateral Retinal Arteritis and Macroaneurysm in Sarcoidosis.

作者信息

Mahmoudzadeh Raziyeh, Gopal Anand, Soares Rebecca, Dunn James P

机构信息

The Retina Service of Wills Eye Hospital, Mid Atlantic Retina, Philadelphia, Pennsylvania, USA.

出版信息

Ocul Immunol Inflamm. 2022 Oct-Nov;30(7-8):1901-1905. doi: 10.1080/09273948.2021.1970780. Epub 2021 Aug 31.

Abstract

BACKGROUND

Sarcoidosis, an idiopathic systemic disorder characterized by noncaseating granulomas, is often associated with granulomatous uveitis. Anterior segment involvement can present with mutton-fat keratic precipitates, anterior chamber cell, and iris nodules. Sarcoid associated posterior uveitis may present with vitritis, retinal vasculitis, and choroidal lesions.

CASE SUMMARY

Sarcoid-associated retinal vasculitis is classically thought of as predominantly involving veins, but in this case report we describe a 76-year-old Caucasian woman presenting with bilateral posterior uveitis, unilateral optic nerve head granuloma, and retinal arteritis as the first manifestation of ocular involvement in systemic sarcoidosis.

CONCLUSION

This case describes the uncommon first manifestation of ocular involvement in systemic sarcoidosis presenting with unilateral retinal arteritis, macroaneurysms and optic nerve head granuloma.

摘要

背景

结节病是一种以非干酪样肉芽肿为特征的特发性全身性疾病,常与肉芽肿性葡萄膜炎相关。前段受累可表现为羊脂状角膜后沉着物、前房细胞和虹膜结节。结节病相关的后葡萄膜炎可能表现为玻璃体炎、视网膜血管炎和脉络膜病变。

病例摘要

结节病相关的视网膜血管炎传统上被认为主要累及静脉,但在本病例报告中,我们描述了一名76岁的白种女性,其双侧后葡萄膜炎、单侧视神经乳头肉芽肿和视网膜动脉炎是系统性结节病眼部受累的首发表现。

结论

本病例描述了系统性结节病眼部受累的罕见首发表现,表现为单侧视网膜动脉炎、大动脉瘤和视神经乳头肉芽肿。

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