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在一家三级医院中过敏性鼻炎的气传过敏原患病率。

Prevalence of Aeroallergens in Allergic Rhinitis in a Tertiary Care Hospital.

机构信息

Department of Otorhinolaryngology and Head and Neck Surgery, Kathmandu University School of Medical Sciences Dhulikhel Hospital, Dhulikhel, Kavre, Nepal.

Department of Dermatology, Kathmandu University School of Medical Sciences Dhulikhel Hospital, Dhulikhel, Kavre, Nepal.

出版信息

JNMA J Nepal Med Assoc. 2020 Nov 22;58(231):866-870. doi: 10.31729/jnma.5218.

Abstract

INTRODUCTION

The prevalence of allergic rhinitis has increased significantly globally over the last two decades. Detection of sensitizing aeroallergens plays a crucial role in the diagnosis and management of this troublesome disease. This study aims to investigate the spectrum of aeroallergens sensitization in patients with allergic rhinitis in a tertiary care hospital.

METHODS

A descriptive cross-sectional study conducted in the Department of Otorhinolaryngology of our hospital between January 2016 to December 2019. Ethical approval was taken from the Institutional Review Committee (No: 210/19). Patients diagnosed with allergic rhinitis were enrolled using the convenience sampling technique. Data entry and analysis was done using IBM Statistical Package for Social Sciences version 20.0.

RESULTS

Among 170 patients, altogether 103 (60.6%) patients yielded positive responses on the skin prick test. The most prevalent aeroallergens were Lepidoglyphus 86 (50.60%), Dermatophagoides pteronyssinus 85 (50%), Dermatophagoides farina 82 (48.20%), Thyrophagus 50 (29.40%), Blomia 46 (27.10%), Acarus 43 (25.30%), cat dander 26 (15.30%), dog dander 24 (14.10%), cow and buffalo dander 20 (11.8%), ragweed 20 (11.8%), grass pollen 18 (10.60%) and mugwort 17 (10%).

CONCLUSIONS

This study highlights that the frequency of aeroallergens based on skin prick test in patients presenting to a tertiary care hospital which showed the dominance of house dust mites, dog and cat hair, pollen, and grasses. Reduced exposure and training of patients about protection against these agents will possibly help in controlling the severity of allergic rhinitis in this region.

摘要

简介

在过去的二十年中,过敏性鼻炎在全球的患病率显著增加。过敏原的检测在这种棘手疾病的诊断和管理中起着至关重要的作用。本研究旨在调查三级医院过敏性鼻炎患者的过敏原致敏谱。

方法

这是一项在我院耳鼻喉科进行的描述性横断面研究,时间为 2016 年 1 月至 2019 年 12 月。该研究获得了机构审查委员会的伦理批准(编号:210/19)。采用便利抽样技术招募过敏性鼻炎患者。使用 IBM 统计软件包(版本 20.0)进行数据录入和分析。

结果

在 170 名患者中,共有 103 名(60.6%)患者的皮肤点刺试验呈阳性反应。最常见的过敏原是 Lepidoglyphus 86(50.60%)、Dermatophagoides pteronyssinus 85(50%)、Dermatophagoides farina 82(48.20%)、Thyrophagus 50(29.40%)、Blomia 46(27.10%)、Acarus 43(25.30%)、猫皮屑 26(15.30%)、狗皮屑 24(14.10%)、牛和水牛皮屑 20(11.8%)、豚草 20(11.8%)、草花粉 18(10.60%)和艾蒿 17(10%)。

结论

本研究表明,在三级医院就诊的患者中,基于皮肤点刺试验的过敏原频率显示出屋尘螨、狗和猫毛、花粉和草的主导地位。减少患者对这些过敏原的接触和培训可能有助于控制该地区过敏性鼻炎的严重程度。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2043/7775014/45f77c1fff00/JNMA-58-231-866-g1.jpg

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