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结肠镜检查前肠道准备导致症状性低钠血症:病例报告。

Symptomatic Hyponatremia following Bowel Preparation for Colonoscopy: A Case Report.

机构信息

Department of Anaesthesiology, Maharajgunj Medical Campus, Maharjgunj, Kathmandu, Nepal.

Department of Critical Care Medicine, Om Hospital and Research Centre, Chabahil, Kathmandu, Nepal.

出版信息

JNMA J Nepal Med Assoc. 2020 Nov 22;58(231):938-940. doi: 10.31729/jnma.5039.

Abstract

Colonoscopy is considered a gold standard tool for the diagnostic evaluation of colorectal diseases. Bowel preparation, a pre-requisite for colonoscopy, usually involves ingestion of purgatives for the cleansing of the bowel so that visualization is not obscured during the procedure. Commonly used preparations are sodium phosphate-based solutions, sodium picosulphate and polyethylene glycol. The use of such preparations is associated with electrolyte disturbances, commonly hyponatremia. Hyponatremia is usually seen with sodium phosphate based solutions and is rare with polyethylene glycol. Symptomatic hyponatremia, however, is rare following bowel preparation and is attributable to other factors as well, such as the age of patient, non-osmotic release of antidiuretic hormone and the procedure itself. In this report, we discuss a case of severe symptomatic hyponatremia observed in a 71-year-old gentleman who underwent polyethylene glycol based bowel preparation for colonoscopy.

摘要

结肠镜检查被认为是诊断评估结直肠疾病的金标准工具。肠道准备是结肠镜检查的前提,通常需要服用泻药来清洁肠道,以避免在检查过程中出现视觉干扰。常用的准备药物包括基于磷酸钠的溶液、匹可硫酸钠和聚乙二醇。使用这些药物会引起电解质紊乱,通常是低钠血症。基于磷酸钠的溶液会引起低钠血症,而聚乙二醇则很少引起。然而,结肠镜检查后出现症状性低钠血症较为罕见,也可能与其他因素有关,如患者年龄、抗利尿激素的非渗透性释放和检查本身。在本报告中,我们讨论了一位 71 岁男性患者的严重症状性低钠血症病例,该患者接受了基于聚乙二醇的肠道准备以进行结肠镜检查。

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