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使用高敏心肌肌钙蛋白I的ESC 0/2小时算法在心肌梗死早期诊断中的性能

Performance of the ESC 0/2h-algorithm using high-sensitivity cardiac troponin I in the early diagnosis of myocardial infarction.

作者信息

Koechlin Luca, Boeddinghaus Jasper, Nestelberger Thomas, Lopez-Ayala Pedro, Wussler Desiree, Shrestha Samyut, Resa Tobias, Wildi Karin, Bakula Adam, Frey Simon, Miró Òscar, Martin-Sanchez F Javier, Strebel Ivo, Gualandro Danielle M, Eckstein Friedrich S, Reuthebuch Oliver, Keller Dagmar I, Twerenbold Raphael, Giménez Maria Rubini, Mueller Christian

机构信息

Cardiovascular Research Institute Basel (CRIB) and Department of Cardiology, University Hospital Basel, University of Basel, Basel, Switzerland; Department of Cardiac Surgery, University Hospital Basel, University of Basel, Basel, Switzerland; GREAT network.

Cardiovascular Research Institute Basel (CRIB) and Department of Cardiology, University Hospital Basel, University of Basel, Basel, Switzerland; GREAT network.

出版信息

Am Heart J. 2021 Dec;242:132-137. doi: 10.1016/j.ahj.2021.08.008. Epub 2021 Sep 9.

Abstract

The 2020 guidelines of the European Society of Cardiology (ESC) recommend a novel ESC 0/2h-algorithm as the preferred alternative to the ESC 0/1h-algorithm in the early triage for rule-out and/or rule-in of Non-ST-segment-elevation myocardial infarction (NSTEMI). The aim was to prospectively validate the performance of the ESC 0/2h-algorithm using the high-sensitivity cardiac troponin I (hs-cTnI) assay (ARCHITECT) in an international, multicenter diagnostic study enrolling patients presenting with acute chest discomfort to the emergency department.

摘要

欧洲心脏病学会(ESC)2020年指南推荐一种新型的ESC 0/2小时算法,作为在非ST段抬高型心肌梗死(NSTEMI)排除和/或确诊的早期分诊中,ESC 0/1小时算法的首选替代方案。目的是在一项国际多中心诊断研究中,使用高敏心肌肌钙蛋白I(hs-cTnI)检测法(ARCHITECT)对ESC 0/2小时算法的性能进行前瞻性验证,该研究纳入了因急性胸痛到急诊科就诊的患者。

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