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医疗机构内病毒大流行期间气溶胶传播程序中的气道管理临床建议。

Clinical recommendations for in-hospital airway management during aerosol-transmitting procedures in the setting of a viral pandemic.

机构信息

Department of Anaesthesiology and Pain Medicine, Inselspital, Bern University Hospital, University of Bern, Freiburgstrasse, CH-3010 Bern, Switzerland.

Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.

出版信息

Best Pract Res Clin Anaesthesiol. 2021 Oct;35(3):333-349. doi: 10.1016/j.bpa.2020.12.002. Epub 2020 Dec 8.

DOI:10.1016/j.bpa.2020.12.002
PMID:34511223
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7723398/
Abstract

The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), can lead to severe pneumonia and multiorgan failure. While most of the infected patients develop no or only mild symptoms, some need respiratory support or even invasive ventilation. The exact route of transmission is currently under investigation. While droplet exposure and direct contact seem to be the most significant ways of transmitting the disease, aerosol transmission appears to be possible under circumstances favored by high viral load. Despite the use of personal protective equipment (PPE), this situation potentially puts healthcare workers at risk of infection, especially if they are involved in airway management. Various recommendations and international guidelines aim to protect healthcare workers, although evidence-based research confirming the benefits of these approaches is still scarce. In this article, we summarize the current literature and recommendations for airway management of COVID-19 patients.

摘要

新型冠状病毒病(COVID-19)是由严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)引起的,可导致严重肺炎和多器官衰竭。虽然大多数感染患者无症状或症状较轻,但有些患者需要呼吸支持甚至有创通气。目前正在调查其确切的传播途径。飞沫暴露和直接接触似乎是传播疾病的最重要途径,但在高病毒载量的情况下,气溶胶传播似乎是可能的。尽管使用了个人防护设备(PPE),但这种情况仍使医护人员面临感染的风险,特别是如果他们参与气道管理。各种建议和国际指南旨在保护医护人员,但仍缺乏证实这些方法益处的基于证据的研究。在本文中,我们总结了 COVID-19 患者气道管理的当前文献和建议。

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Clinical recommendations for in-hospital airway management during aerosol-transmitting procedures in the setting of a viral pandemic.医疗机构内病毒大流行期间气溶胶传播程序中的气道管理临床建议。
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本文引用的文献

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PLoS One. 2020 Nov 3;15(11):e0241536. doi: 10.1371/journal.pone.0241536. eCollection 2020.
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4
Timing, Complications, and Safety of Tracheotomy in Critically Ill Patients With COVID-19.新型冠状病毒肺炎(COVID-19)危重症患者气管切开术的时机、并发症及安全性
JAMA Otolaryngol Head Neck Surg. 2020 Oct 8;147(1):1-8. doi: 10.1001/jamaoto.2020.3641.
5
A quantitative evaluation of aerosol generation during tracheal intubation and extubation.气管插管和拔管过程中气溶胶产生的定量评估。
Anaesthesia. 2021 Feb;76(2):174-181. doi: 10.1111/anae.15292. Epub 2020 Oct 22.
6
Aerosol boxes and barrier enclosures for airway management in COVID-19 patients: a scoping review and narrative synthesis.用于 COVID-19 患者气道管理的气溶胶盒和屏障围闭装置:范围综述和叙述性综合。
Br J Anaesth. 2020 Dec;125(6):880-894. doi: 10.1016/j.bja.2020.08.038. Epub 2020 Sep 3.
7
Airway management and COVID-19 patient -Saudi Anesthesia Society guidelines.气道管理与新冠肺炎患者——沙特麻醉学会指南
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Retrospective analysis of high flow nasal therapy in COVID-19-related moderate-to-severe hypoxaemic respiratory failure.回顾性分析高流量鼻导管通气在 COVID-19 相关中重度低氧血症性呼吸衰竭中的应用。
BMJ Open Respir Res. 2020 Aug;7(1). doi: 10.1136/bmjresp-2020-000650.
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Anaesthesia. 2021 Feb;76(2):251-260. doi: 10.1111/anae.15253. Epub 2020 Sep 13.
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Perioper Care Oper Room Manag. 2020 Sep;20:100122. doi: 10.1016/j.pcorm.2020.100122. Epub 2020 Jun 18.