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基于病毒载量的空间网络传染病传播模型

A viral load-based model for epidemic spread on spatial networks.

机构信息

Department of Mathematical Sciences "G. L. Lagrange", Politecnico di Torino, Italy.

出版信息

Math Biosci Eng. 2021 Jun 23;18(5):5635-5663. doi: 10.3934/mbe.2021285.

Abstract

In this paper, we propose a Boltzmann-type kinetic model of the spreading of an infectious disease on a network. The latter describes the connections among countries, cities or districts depending on the spatial scale of interest. The disease transmission is represented in terms of the viral load of the individuals and is mediated by social contacts among them, taking into account their displacements across the nodes of the network. We formally derive the hydrodynamic equations for the density and the mean viral load of the individuals on the network and we analyse the large-time trends of these quantities with special emphasis on the cases of blow-up or eradication of the infection. By means of numerical tests, we also investigate the impact of confinement measures, such as quarantine or localised lockdown, on the diffusion of the disease on the network.

摘要

在本文中,我们提出了一种用于网络上传染病传播的玻尔兹曼型动理学模型。该模型描述了根据感兴趣的空间尺度而存在的国家、城市或地区之间的联系。疾病传播是通过个体的病毒载量来表示的,并且通过考虑他们在网络节点之间的移动来介导社交接触。我们正式推导出网络上个体密度和平均病毒载量的流体力学方程,并分析了这些量的长时间趋势,特别强调了感染爆发或根除的情况。通过数值测试,我们还研究了隔离措施(如检疫或局部封锁)对网络上疾病传播的影响。

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