[Detection of oropharyngeal sensory function in normal population].

To study the oropharyngeal sensory function by Current Perception Threshold(CPT) detection, to explore the detection method of oropharyngeal sensory function in normal population, and to analyze the possible influencing factors. Fifty-eight normal subjects were included prospectively in this study. Age, gender, body mass index (BMI) were collected. The age of the subjects ranged from 20 to 76 (43.27±13.52) years old. There were 34 females with 17 in childbearing period and 17 in menopause; and 24 males were included.In all the cases, 6 cases were in low BMI, 39 cases were in normal BMI, 10 cases were overweight and 3 cases were suffering from obesity. The CPT system of Neurometer was used to stimulate bilateral palatoglossal arch and tongue base.The current used was 2000 Hz, 250 Hz and 5 Hz respectively.The function of type Aβ, Aδ and C sensory nerve fibers were tested and the CPT values were recorded.The values were inversely proportional to pharyngeal sensation function.To evaluate the oropharyngeal sensory function of the subjects, the CPT values of each frequency at each testing point were compared. SPSS 25.0 software was used for statistical analysis. The CPT value of palatoglossal arch was significantly lower than that of tongue base (=-2.58,-2.65,-2.54,-2.47,-2.37,-2.77,<0.05), 2 000 Hz>250 Hz>5 Hz, and there was no significant difference between left and right sides(=-0.03,-0.51,-0.49,0.06,-0.16,0.13,>0.05). The CPT value of male was slightly higher than that of female (=0.92,1.55,0.27,0.78,1.44,1.26,0.35,0.77,1.27,0.24,0.78,0.96,>0.05). The CPT values of women in childbearing period were significantly less than those in menopausal women (=-3.90,-3.64,-2.14,-4.20,-4.28,-4.28,-3.52,-4.46,-3.41,-3.63,-4.66,-2.86,<0.05). The CPT value increased with age, and the values of all frequency of 20 to 30 years old group was significantly lower than those of subjects over 40 years old at each point (The values of bilateral palatoglossal arch at 2 000 Hz were -5.57,-6.22,-10.18,-11.00;the values of bilateral palatoglossal arch at 250 Hz were -6.39,-8.79,-6.39,-15.61;the values of bilateral palatoglossal arch at 5 Hz were -7.09, -5.57, -9.26, -15.23;the values of tongue base at 2 000 Hz were -3.11,-3.88,-7.60,-8.55;the values of tongue base at 250 Hz were -6.31,-10.59,-8.52,-10.60;the values of tongue baseat 5 Hz were -6.69,-5.09,-8.70,-7.07,<0.05).The values at all frequencies and testing points of 30-40 years old group were significantly lower than those of all subjects over 60 years old (The values of bilateral palatoglossal arch at 2 000 Hz were -10.91,-12.42;the values of bilateral palatoglossal arch at 250 Hz were -6.25,-10.87;the values of bilateral palatoglossal arch at 5 Hz were -5.53,-11.01;the values of tongue base at 2 000 Hz were -8.62,-10.12;the values of tongue base at 250 Hz were -6.89,-7.82;the values of tongue base at 5 Hz were -6.13,-6.48,<0.05). CPT can be used to evaluate oropharyngeal sensory function. The sensitivity of tongue base is lower than that of palatoglossal arch, there is no significant difference in oropharyngeal sensory function between male and female,between left and right sides. There are many factors influencing oropharyngeal sensory function. Age, hormone level changes may affect the sensitivity of oropharyngeal sensory function.