Department of Cardiology, National Center for Global Health and Medicine, Tokyo, Japan.
Department of Cardiology, National Center for Global Health and Medicine, Tokyo, Japan.
J Cardiol. 2022 Apr;79(4):460-467. doi: 10.1016/j.jjcc.2021.09.010. Epub 2021 Sep 15.
The COVID-19 pandemic has rapidly emerged as one of the biggest public health concerns of the 21st century. Although it was initially reported as a cluster of pneumonia cases, it quickly became apparent that COVID-19 is not merely a respiratory tract infection. Its clinical course is often complicated by cardiovascular manifestations including venous and arterial thrombosis, electrical disturbances, and myocardial damage. In addition, the cardiovascular system is involved not only during infection but also preceding the contraction of the virus; having cardiovascular comorbidities indicates significant vulnerability to the pathogen. As longer-term data continue to accumulate, we now have concerns over its lasting cardiovascular effects after recovery. Moreover, there have been substantial collateral effects on the epidemiology of cardiovascular diseases. Reports of adverse cardiovascular events from vaccination have emerged as new hurdles to our efforts to bring an end to the pandemic. As such, the association between COVID-19 and the cardiovascular system and cardiovascular practice in general is expansive. In this review, we provide an overview of the knowledge and considerations in this field, based on the evidence available at the time of this writing.
新冠疫情迅速成为 21 世纪公共卫生领域最大的关注点之一。虽然最初报告的是一组肺炎病例,但很快就清楚地表明,新冠疫情不仅仅是一种呼吸道感染。其临床过程通常会伴有心血管表现,包括静脉和动脉血栓形成、电紊乱和心肌损伤。此外,心血管系统不仅在感染期间受到影响,而且在病毒收缩之前就已经受到影响;患有心血管合并症表明对病原体的显著易感性。随着更长时间的数据不断积累,我们现在对感染后长期的心血管影响表示担忧。此外,对心血管疾病的流行病学也产生了重大的间接影响。接种疫苗后出现的不良心血管事件报告,给我们结束疫情的努力带来了新的障碍。因此,新冠疫情与心血管系统以及一般心血管实践之间的联系是广泛的。在这篇综述中,我们根据撰写时的现有证据,对这一领域的知识和注意事项进行了概述。