Ogdie Alexis, Matthias Wesley, Thielen Richard J, Chin Daniel, Saffore Christopher D
University of Pennsylvania, Philadelphia, PA, USA.
Health Economics and Outcomes Research, AbbVie Inc., 1 N Waukegan Road, Dept. GMH1, ABV1 4NW-102-04, North Chicago, IL, 60064-6078, USA.
Rheumatol Ther. 2021 Dec;8(4):1725-1739. doi: 10.1007/s40744-021-00370-4. Epub 2021 Sep 25.
Patients with psoriatic arthritis (PsA) and ankylosing spondylitis (AS) may receive suboptimal care, and differences in care by race/ethnicity, sex, and insurance coverage are not well studied.
This was a descriptive, retrospective cross-sectional US claims database analysis utilizing the Medicaid multi-state segment of the IBM® MarketScan® Commercial Claims and Encounters Supplemental Database and Optum Insight Clinformatics® Data Mart database for 2019. Patients aged ≥ 18 years with PsA or AS and continuous medical and pharmacy coverage were included. Outcomes evaluated were prevalence and percentage of patients receiving biologic disease-modifying antirheumatic drugs (bDMARDs)/targeted synthetic DMARDs (tsDMARDs) or visiting a rheumatologist. Outcomes were stratified by race/ethnicity, sex, and insurance coverage, with outcomes determined for commercial insurance, Medicare, and Medicaid enrollees. Differences observed in outcomes were numerical in nature.
Prevalences of PsA and AS were highest for Medicare enrollees (320 and 156 per 100,000 persons [0.32 and 0.16%], respectively) and lowest for Medicaid enrollees (132 and 71 per 100,000 persons [0.13 and 0.07%], respectively). White patients had the greatest prevalence versus patients of other races/ethnicities. Females had a higher prevalence of PsA than males, while AS prevalence was generally lower for females versus males for each insurance category. The percentage of patients prescribed bDMARDs/tsDMARDs was highest for commercial insurance enrollees (PsA 63%, AS 43%) and lowest for Medicare enrollees (PsA 21%, AS 11%). The proportion of patients who saw a rheumatologist was lower for Medicaid enrollees (PsA 12%, AS 10%) than for commercial insurance or Medicare enrollees (PsA 68%, 55%; AS 67%, 42%). For commercial insurance and Medicare enrollees, the percentage of patients visiting a rheumatologist was similar by race/ethnicity but higher for females versus males.
The prevalence and treatment of PsA and AS differs by race/ethnicity, insurance coverage, and sex in the USA. Efforts for improving access to care are needed to improve outcomes among all patients.
银屑病关节炎(PsA)和强直性脊柱炎(AS)患者可能未得到最佳治疗,而关于种族/民族、性别和保险覆盖范围在治疗方面的差异尚未得到充分研究。
这是一项描述性回顾性横断面美国索赔数据库分析,利用IBM® MarketScan®商业索赔和就诊补充数据库的医疗补助多州部分以及Optum Insight Clinformatics®数据集市数据库,数据来自2019年。纳入年龄≥18岁、患有PsA或AS且有持续医疗和药房保险覆盖的患者。评估的结果包括接受生物性抗风湿药物(bDMARDs)/靶向合成DMARDs(tsDMARDs)治疗的患者患病率和百分比,或看风湿病专科医生的患者情况。结果按种族/民族、性别和保险覆盖范围分层,分别确定商业保险、医疗保险和医疗补助参保者的结果。观察到的结果差异本质上是数值性的。
医疗保险参保者中PsA和AS的患病率最高(分别为每10万人320例和156例[0.32%和0.16%]),医疗补助参保者中最低(分别为每10万人132例和71例[0.13%和0.07%])。白人患者的患病率高于其他种族/民族的患者。女性PsA的患病率高于男性,而在每个保险类别中,女性AS的患病率总体低于男性。商业保险参保者中开具bDMARDs/tsDMARDs的患者百分比最高(PsA为63%,AS为43%),医疗保险参保者中最低(PsA为21%,AS为11%)。医疗补助参保者看风湿病专科医生的比例(PsA为12%,AS为10%)低于商业保险或医疗保险参保者(PsA为68%、55%;AS为67%、42%)。对于商业保险和医疗保险参保者,不同种族/民族的患者看风湿病专科医生的百分比相似,但女性高于男性。
在美国,PsA和AS的患病率及治疗情况因种族/民族、保险覆盖范围和性别而异。需要努力改善医疗服务可及性,以改善所有患者的治疗结果。