Department of Microbiology, College of Basic Sciences and Humanities, Punjab Agricultural University, Ludhiana, Punjab, India.
Department of Applied Sciences and Biotechnology, School of Biotechnology, Shoolini University, Solan, Himachal Pradesh, India.
J Appl Microbiol. 2022 Jul;133(1):18-38. doi: 10.1111/jam.15308. Epub 2021 Oct 4.
The present review highlights the advantages of using natural colorant over the synthetic one. We have discussed the fermentation parameters that can enhance the productivity of Monascus pigment on agricultural wastes.
Food industry is looking for natural colours because these can enhance the esthetic value, attractiveness, and acceptability of food while remaining nontoxic. Many synthetic food colours (Azorubine Carmoisine, quinoline) have been prohibited due to their toxicity and carcinogenicity. Increasing consumer awareness towards the food safety has forced the manufacturing industries to look for suitable alternatives. In addition to safety, natural colorants have been found to have nutritional and therapeutic significance. Among the natural colorants, microbial pigments can be considered as a viable option because of scalability, easier production, no seasonal dependence, cheaper raw materials and easier extraction. Fungi such as Monascus have a long history of safety and therefore can be used for production of biopigments.
The present review summarizes the predicted biosynthetic pathways and pigment gene clusters in Monascus purpureus.
The challenges faced during the pilot-scale production of Monascus biopigment and taming it by us of low-cost agro-industrial substrates for solid state fermentation has been suggested.
Keeping in mind, therapeutic properties of Monascus pigments and their derivatives, they have huge potential for industrial and pharmaceutical application.
Though the natural pigments have wide scope in the food industry. However, stabilization of pigment is the greatest challenge and attempts are being made to overcome this by complexion with hydrocolloids or metals and by microencapsulation.
本综述强调了使用天然着色剂而非合成着色剂的优势。我们讨论了可以提高红曲菌色素在农业废弃物上产量的发酵参数。
食品工业正在寻找天然色素,因为这些色素可以提高食品的美观、吸引力和可接受性,同时保持无毒。由于毒性和致癌性,许多合成食用色素(偶氮玉红、胭脂红)已被禁止。消费者对食品安全意识的提高迫使制造行业寻找合适的替代品。除了安全性之外,天然着色剂还被发现具有营养和治疗意义。在天然着色剂中,由于可扩展性、更容易生产、不受季节性影响、原材料更便宜且更容易提取,微生物色素可以被认为是一种可行的选择。红曲菌等真菌因其安全性而具有悠久的历史,因此可用于生产生物色素。
本综述总结了红曲菌中预测的生物合成途径和色素基因簇。
提出了在红曲菌生物色素的中试生产中面临的挑战,并建议使用低成本的农业工业基质对其进行固态发酵驯化。
考虑到红曲菌色素及其衍生物的治疗特性,它们在工业和制药应用方面具有巨大的潜力。
虽然天然色素在食品工业中有广泛的应用前景。然而,色素的稳定性是最大的挑战,人们正在尝试通过与水胶体或金属络合以及微胶囊化来克服这一问题。