长期新冠与超重/肥胖之间的关联。
Association between Long COVID and Overweight/Obesity.
作者信息
Vimercati Luigi, De Maria Luigi, Quarato Marco, Caputi Antonio, Gesualdo Loreto, Migliore Giovanni, Cavone Domenica, Sponselli Stefania, Pipoli Antonella, Inchingolo Francesco, Scarano Antonio, Lorusso Felice, Stefanizzi Pasquale, Tafuri Silvio
机构信息
Interdisciplinary Department of Medicine, Section of Occupational Medicine, University of Bari, 70124 Bari, Italy.
Occupational Medicine Unit, University Hospital of Bari, 70124 Bari, Italy.
出版信息
J Clin Med. 2021 Sep 14;10(18):4143. doi: 10.3390/jcm10184143.
BACKGROUND
Long COVID is a syndrome characterized by the persistence of SARS-CoV-2 infection symptoms. Among HCWs, prolonged COVID symptoms could lead to the inability to perform work tasks. The aim of this study is to investigate 35-day long-COVID (35-LC) characteristics and risk factors in a one-year period.
METHODS
We carried out a retrospective cohort study during the COVID-19 pandemic at University Hospital of Bari. A total of 5750 HCWs were tested for close contact with a confirmed case, in the absence of personal protective equipment, or for symptom development.
RESULTS
Each positive HCW was investigated for cardiovascular risk factors or respiratory diseases. An amount of 352 HCWs (6.1%) were infected by SARS-CoV-2, and 168 cases evolved to long COVID. The 35-LC group showed mean BMI values higher than the non-35-LC group (25.9 kg/m vs. 24.8 kg/m, respectively), and this difference was significant (-value: 0.020). Moreover, HCWs who suffered from pulmonary disease (OR = 3.7, CL 95%: 1.35-10.53; -value = 0.007) or overweight (OR = 1.6 CL 95%: 1.05-2.56; -value = 0.029) had an increased risk of developing 35-LC.
CONCLUSIONS
Long COVID is an emerging problem for hospital managers as it may reduce the number of HCWs deployed in the fight against COVID-19. High BMI and previous pulmonary disease could be risk factors for 35-LC development in exposed HCWs.
背景
新冠后综合征是一种以严重急性呼吸综合征冠状病毒2（SARS-CoV-2）感染症状持续存在为特征的综合征。在医护人员中，新冠后症状持续时间延长可能导致无法完成工作任务。本研究的目的是调查一年内35天新冠后综合征（35-LC）的特征和危险因素。
方法
我们在巴里大学医院的新冠疫情期间进行了一项回顾性队列研究。共有5750名医护人员因与确诊病例密切接触、未佩戴个人防护装备或出现症状而接受检测。
结果
对每例呈阳性的医护人员都进行了心血管危险因素或呼吸系统疾病调查。352名医护人员（6.1%）感染了SARS-CoV-2，其中168例发展为新冠后综合征。35-LC组的平均体重指数值高于非35-LC组（分别为25.9kg/m²和24.8kg/m²），且这种差异具有统计学意义（P值：0.020）。此外，患有肺部疾病（比值比[OR]=3.7，95%置信区间[CL]：1.35-10.53；P值=0.007）或超重（OR=1.6，CL 95%：1.05-2.56；P值=0.029）的医护人员发生35-LC的风险增加。
结论
新冠后综合征对医院管理者来说是一个新出现的问题，因为它可能会减少参与抗击新冠疫情的医护人员数量。高体重指数和既往肺部疾病可能是接触新冠病毒的医护人员发生35-LC的危险因素。
Zotero 插件