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一项针对患有抑郁症父母的子女的家庭组认知行为(FGCB)预防性干预的随机对照试验:对症状的短期影响及可能机制

A randomised controlled trial of a family-group cognitive-behavioural (FGCB) preventive intervention for the children of parents with depression: short-term effects on symptoms and possible mechanisms.

作者信息

Löchner Johanna, Starman-Wöhrle Kornelija, Takano Keisuke, Engelmann Lina, Voggt Alessandra, Loy Fabian, Bley Mirjam, Winogradow Dana, Hämmerle Stephanie, Neumeier Esther, Wermuth Inga, Schmitt Katharina, Oort Frans, Schulte-Körne Gerd, Platt Belinda

机构信息

Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital, Ludwig-Maximilians-University, Munich, Germany.

German Youth Institute (Deutsches Jugendinstitut E.V.), Munich, Germany.

出版信息

Child Adolesc Psychiatry Ment Health. 2021 Oct 1;15(1):54. doi: 10.1186/s13034-021-00394-2.

Abstract

OBJECTIVE

Parental depression is one of the biggest risk factors for youth depression. This parallel randomized controlled trial evaluates the effectiveness of the German version of the family-group-cognitive-behavioral (FGCB) preventive intervention for children of depressed parents.

METHODS

Families with (i) a parent who has experienced depression and (ii) a healthy child aged 8-17 years (mean = 11.63; 53% female) were randomly allocated (blockwise; stratified by child age and parental depression) to the 12-session intervention (EG; n = 50) or no intervention (CG; usual care; n = 50). Self-reported (unblinded) outcomes were assessed immediately after the intervention (6 months). We hypothesized that CG children would show a greater increase in self-reported symptoms of depression (DIKJ) and internalising/externalising disorder (YSR/CBCL) over time compared to the EG. Intervention effects on secondary outcome variables emotion regulation (FEEL-KJ), attributional style (ASF-KJ), knowledge of depression and parenting style (ESI) were also expected. Study protocol (Belinda Platt, Pietsch, Krick, Oort, & Schulte-Körne, 2014) and trial registration (NCT02115880) reported elsewhere.

RESULTS

We found significant intervention effects on self-reported internalising ([Formula: see text] = 0.05) and externalising ([Formula: see text] = 0.08) symptoms but did not detect depressive symptoms or parent-reported psychopathology. Parental depression severity did not modify these effects. Both groups showed equally improved knowledge of depression ([Formula: see text] = 0.06). There were no intervention effects on emotion regulation, attributional style or parenting style.

CONCLUSION

The German version of the FGCB intervention is effective in reducing symptoms of general psychopathology. There was no evidence that the mechanisms targeted in the intervention changed within the intervention period.

摘要

目的

父母抑郁是青少年抑郁的最大风险因素之一。这项平行随机对照试验评估了德文版家庭团体认知行为(FGCB)预防干预措施对抑郁父母子女的有效性。

方法

招募符合以下条件的家庭:(i)有一位经历过抑郁的父母;(ii)有一个8至17岁的健康孩子(平均年龄 = 11.63岁;53%为女性),将其随机分配(按年龄组;根据孩子年龄和父母抑郁情况分层)至12节干预课程组(实验组,EG;n = 50)或无干预组(对照组,CG;常规护理;n = 50)。干预结束后(6个月)立即评估自我报告(非盲法)的结果。我们假设,与实验组相比,对照组儿童随着时间推移自我报告的抑郁症状(DIKJ)和内化/外化障碍(YSR/CBCL)会有更大幅度的增加。预计干预对次要结果变量情绪调节(FEEL-KJ)、归因方式(ASF-KJ)、抑郁知识和养育方式(ESI)也有影响。研究方案(贝琳达·普拉特、皮茨、克里克、奥尔特和舒尔特 - 克内,2014年)及试验注册情况(NCT02115880)在其他地方报道。

结果

我们发现干预对自我报告的内化症状([公式:见原文] = 0.05)和外化症状([公式:见原文] = 0.08)有显著影响,但未检测到抑郁症状或父母报告的精神病理学问题。父母抑郁严重程度并未改变这些影响。两组在抑郁知识方面均有同等程度的改善([公式:见原文] = 0.06)。干预对情绪调节、归因方式或养育方式没有影响。

结论

德文版FGCB干预措施在减轻一般精神病理学症状方面有效。没有证据表明干预期间所针对的机制发生了变化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f76/8487152/b792759ec116/13034_2021_394_Fig1_HTML.jpg

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