Division of Vascular and Endovascular Surgery, Department of Surgery, University of Virginia Health System, Charlottesville, VA.
Division of Vascular and Endovascular Surgery, Department of Surgery, University of Virginia Health System, Charlottesville, VA.
Tech Vasc Interv Radiol. 2021 Jun;24(2):100749. doi: 10.1016/j.tvir.2021.100749. Epub 2021 Jul 24.
For decades, the mainstay of management for acute, uncomplicated type B aortic dissection (TBAD) has been anti-impulse medical therapy, focusing on close control of blood pressure, and heart rate. However, the natural history of this entity has remained one of aortic degeneration over time and significant morbidity and mortality. More recently, the advent of endovascular therapy has driven a revolution in the management of TBAD. While thoracic endovascular aortic repair (TEVAR) was rapidly adopted for the treatment of complicated type B aortic dissection due to significantly improved morbidity and mortality when compared with tradition open surgical techniques, its role in the management of uncomplicated dissection remained controversial. However, the accumulation of favorable data on aortic remodeling and survival following early TEVAR for uncomplicated dissection is driving a shift in paradigm and practice. This is particularly true of patients exhibiting certain features at the time of presentation that are associated with increased risk of failure of optimal medical therapy. This article reviews the current evidence in the literature addressing TEVAR for acute, uncomplicated TBAD. In addition, it presents the state of the art in FDA-approved thoracic endograft platforms, guidance regarding case planning, and step-by-step procedural description, including the management of common challenges, and complications.
几十年来,急性、非复杂性 B 型主动脉夹层(TBAD)的主要治疗方法一直是抗冲动药物治疗,重点是密切控制血压和心率。然而,随着时间的推移,这种疾病的自然病程仍然是主动脉退行性变,发病率和死亡率都很高。最近,血管内治疗的出现彻底改变了 TBAD 的治疗方法。虽然胸主动脉腔内修复术(TEVAR)由于与传统的开放性手术技术相比显著降低了发病率和死亡率,因此很快被用于治疗复杂型 B 型主动脉夹层,但它在非复杂性夹层治疗中的作用仍然存在争议。然而,大量关于早期 TEVAR 治疗非复杂性夹层后主动脉重塑和生存的有利数据正在推动观念和实践的转变。对于在发病时具有某些特征的患者尤其如此,这些特征与最佳药物治疗失败的风险增加有关。本文回顾了目前关于急性、非复杂性 TBAD 的 TEVAR 的文献证据。此外,本文还介绍了经过 FDA 批准的胸主动脉腔内移植物平台的最新技术、病例规划和逐步手术描述方面的指导,包括常见挑战和并发症的处理。