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髌骨脱位患者非手术治疗、内侧髌股韧带修复与内侧髌股韧带重建的比较:一项系统评价和网状Meta分析

Comparing Nonoperative Treatment, MPFL Repair, and MPFL Reconstruction for Patients With Patellar Dislocation: A Systematic Review and Network Meta-analysis.

作者信息

Liu Zhongcheng, Yi Qiong, He Liangzhi, Yao Changjiang, Zhang Lanfang, Lu Fan, Zhang Xiaohui, Wu Meng, Geng Bin, Xia Yayi, Jiang Jin

机构信息

Department of Orthopaedics, Gansu Key Laboratory of Orthopaedics, Lanzhou University Second Hospital, Lanzhou, Gansu, PR China.

Department of Neurosurgery, Lanzhou University Second Hospital, Lanzhou, Gansu, PR China.

出版信息

Orthop J Sports Med. 2021 Sep 28;9(9):23259671211026624. doi: 10.1177/23259671211026624. eCollection 2021 Sep.

Abstract

BACKGROUND

Medial patellofemoral ligament (MPFL) reconstruction, MPFL repair, and nonoperative treatment are important treatments for patients with patellar dislocation. However, it is unclear which treatment leads to better outcomes.

PURPOSE

To determine the efficacy and safety of the 3 treatments in the treatment of patellar dislocation and compare the effect of MPFL reconstruction with MPFL repair, MPFL reconstruction with nonoperative treatment, and MPFL repair with nonoperative treatment.

STUDY DESIGN

Systematic review; Level of evidence, 3.

METHODS

The PubMed, Web of Science, Cochrane Library, Embase, CNKI (China National Knowledge Infrastructure), and Wanfang databases were searched from inception to December 2020. Included were clinical studies that described the efficacy and safety of 2 of the 3 treatments, studies directly comparing the clinical effects of the 2 operative techniques, or studies comparing the effects of reconstruction or repair with nonoperative treatment. Two reviewers independently extracted data and assessed the quality of the included studies with the Cochrane risk-of-bias tools. The outcomes evaluated were postoperative redislocation rate, revision rate, complications, and Kujala score. We used traditional direct pairwise meta-analysis as well as network meta-analysis for comprehensive efficacy of all 3 treatment measures.

RESULTS

Twelve studies were included: 5 compared MPFL reconstruction with MPFL repair, 2 compared MPFL reconstruction with nonoperative treatment, and 5 compared MPFL repair with nonoperative treatment. The risk of bias was serious in 4, moderate in 4 and low in 4 articles. MPFL reconstruction led to significantly reduced redislocation and improved Kujala scores compared with MPFL repair and nonoperative treatment. MPFL repair led to reduced redislocation rates compared with nonoperative treatment but did not show an obvious benefit in primary dislocations. There was no significant difference among the 3 treatments in terms of revision rate and incidence of complications, although we found that treatment-related complications were least likely to occur in nonoperative treatment.

CONCLUSION

The results of this review indicate that MPFL reconstruction decreases recurrent dislocation compared with MPFL repair or nonoperative treatment, but it has a higher possibility of complications. MPFL repair resulted in less postoperative redislocation than nonoperative treatment but did not show an obvious benefit in primary dislocation.

摘要

背景

髌股内侧韧带(MPFL)重建、MPFL修复及非手术治疗是髌骨脱位患者的重要治疗方法。然而,尚不清楚哪种治疗方法能带来更好的疗效。

目的

确定这三种治疗方法治疗髌骨脱位的有效性和安全性,并比较MPFL重建与MPFL修复、MPFL重建与非手术治疗以及MPFL修复与非手术治疗的效果。

研究设计

系统评价;证据等级,3级。

方法

检索PubMed、科学网、Cochrane图书馆、Embase、中国知网(CNKI)和万方数据库,检索时间从建库至2020年12月。纳入描述三种治疗方法中两种方法的有效性和安全性的临床研究、直接比较两种手术技术临床效果的研究,或比较重建或修复与非手术治疗效果的研究。两名评价者独立提取数据,并使用Cochrane偏倚风险工具评估纳入研究的质量。评估的结局指标为术后再脱位率、翻修率、并发症及库贾拉评分。我们使用传统的直接成对荟萃分析以及网状荟萃分析来综合评估所有三种治疗措施的疗效。

结果

共纳入12项研究:5项比较了MPFL重建与MPFL修复,2项比较了MPFL重建与非手术治疗,5项比较了MPFL修复与非手术治疗。4篇文章的偏倚风险严重,4篇为中度,4篇为低度。与MPFL修复和非手术治疗相比,MPFL重建导致再脱位显著减少,库贾拉评分改善。与非手术治疗相比,MPFL修复导致再脱位率降低,但在初次脱位中未显示出明显优势。三种治疗方法在翻修率和并发症发生率方面无显著差异,尽管我们发现与治疗相关的并发症在非手术治疗中发生的可能性最小。

结论

本综述结果表明,与MPFL修复或非手术治疗相比,MPFL重建可降低复发性脱位,但并发症发生的可能性更高。MPFL修复术后再脱位比非手术治疗少,但在初次脱位中未显示出明显优势。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb1e/8485172/fc9def795b88/10.1177_23259671211026624-fig1.jpg

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