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心房颤动、生活质量和困扰:认知和行为反应的聚类分析。

Atrial fibrillation, quality of life and distress: a cluster analysis of cognitive and behavioural responses.

机构信息

Health Psychology Section, Institute of Psychiatry, Psychology and Neuroscience, King's College London, 5th Floor Bermondsey Wing, Guy's Hospital, London Bridge, London, SE1 9RT, UK.

University of Derby, Kedleston Road, Derby, DE22 1GB, UK.

出版信息

Qual Life Res. 2022 May;31(5):1415-1425. doi: 10.1007/s11136-021-03006-w. Epub 2021 Oct 7.

Abstract

PURPOSE

Few studies have examined specific cognitive and behavioural responses to symptoms, which may impact health-related outcomes, in conjunction with illness representations, as outlined by the Common-Sense-Model. Patients with atrial fibrillation (AF) report poor quality-of-life (QoL) and high distress. This cross-sectional study investigated patterns/clusters of cognitive and behavioural responses to illness, and illness perceptions, and relationships with QoL, depression and anxiety.

METHODS

AF patients (N = 198) recruited at cardiology clinics completed the AF-Revised Illness Perception Questionnaire, Atrial-Fibrillation-Effect-on-Quality-of-Life Questionnaire, Patient Health Questionnaire-8 and Generalized Anxiety Disorder Questionnaire. Cluster analysis used Ward's and K-means methods. Hierarchical regressions examined relationships between clusters with QoL, depression and anxiety.

RESULTS

Two clusters of cognitive and behavioural responses to symptoms were outlined; (1) 'high avoidance'; (2) 'low symptom-focussing'. Patients in Cluster 1 had lower QoL (M = 40.36, SD = 18.40), greater symptoms of depression (M = 7.20, SD = 5.71) and greater symptoms of anxiety (M = 5.70, SD = 5.90) compared to patients in Cluster 2 who had higher QoL (M = 59.03, SD = 20.12), fewer symptoms of depression (M = 3.53, SD = 3.56) and fewer symptoms of anxiety (M = 2.56, SD = 3.56). Two illness representation clusters were outlined; (1) 'high coherence and treatment control', (2) 'negative illness and emotional representations'. Patients in Cluster 2 had significantly lower QoL (M = 46.57, SD = 19.94), greater symptoms of depression (M = 6.12, SD = 5.31) and greater symptoms of anxiety (M = 4.70, SD = 5.27), compared with patients in Cluster 1 who had higher QoL (M = 61.52, SD = 21.38), fewer symptoms of depression (M = 2.85, SD = 2.97) and fewer symptoms of anxiety (M = 2.16, SD = 3.63). Overall, clusters of cognitive and behavioural responses to symptoms, and illness perceptions significantly explained between 14 and 29% of the variance in QoL, depression and anxiety.

CONCLUSION

Patterns of cognitive and behavioural responses to symptoms, and illness perceptions are important correlates of health-related outcomes in AF patients.

摘要

目的

很少有研究探讨特定的认知和行为反应症状,这些反应可能会影响与健康相关的结果,同时也会影响疾病的表现,这是通感模型所概述的。心房颤动(AF)患者报告生活质量(QoL)差和高度痛苦。这项横断面研究调查了对疾病的认知和行为反应以及疾病认知的模式/聚类,以及与 QoL、抑郁和焦虑的关系。

方法

在心脏病学诊所招募的 AF 患者(N=198)完成了 AF 修订后的疾病认知问卷、心房颤动对生活质量的影响问卷、患者健康问卷-8 和广泛性焦虑症问卷。聚类分析采用 Ward 和 K-means 方法。层次回归检验了与 QoL、抑郁和焦虑相关的聚类之间的关系。

结果

概述了两种对症状的认知和行为反应模式;(1)“高回避”;(2)“低症状聚焦”。与聚类 2 中的患者相比,聚类 1 中的患者 QoL 更低(M=40.36,SD=18.40),抑郁症状更严重(M=7.20,SD=5.71),焦虑症状更严重(M=5.70,SD=5.90),而聚类 2 中的患者 QoL 更高(M=59.03,SD=20.12),抑郁症状更少(M=3.53,SD=3.56),焦虑症状更少(M=2.56,SD=3.56)。概述了两种疾病认知聚类;(1)“高一致性和治疗控制”,(2)“负面疾病和情绪认知”。与聚类 1 中的患者相比,聚类 2 中的患者 QoL 显著更低(M=46.57,SD=19.94),抑郁症状更严重(M=6.12,SD=5.31),焦虑症状更严重(M=4.70,SD=5.27),而聚类 1 中的患者 QoL 更高(M=61.52,SD=21.38),抑郁症状更少(M=2.85,SD=2.97),焦虑症状更少(M=2.16,SD=3.63)。总的来说,对症状的认知和行为反应以及疾病认知的聚类,在 QoL、抑郁和焦虑方面解释了 14%至 29%的方差。

结论

对症状的认知和行为反应模式以及疾病认知是 AF 患者健康相关结果的重要相关因素。

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